产品展示
磷酸化热休克蛋白27抗体 田源一抗磷酸化抗体
点击次数:166发布时间:2012/8/5 0:17:00
更新日期:2013/6/8 9:48:41
所 在 地:其它
产品型号:Anti-Phospho-HSP27 (Ser82)
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详细内容
磷酸化热休克蛋白27抗体Anti-Phospho-HSP27 (Ser82)HSP27(Phospho-Ser82); Heat shock 27kDa protein 1; Heat shock 28kDa protein 1; Heat Shock P
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性能参数:
中文名称:磷酸化热休克蛋白27抗体
英文名称:Anti-Phospho-HSP27 (Ser82)
别名:HSP27(Phospho-Ser82); Heat shock 27kDa protein 1; Heat shock 28kDa protein 1; Heat Shock P
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found, but only one transcript variant has been supported and defined. [provided by RefSeq].Hsp27, also referred to as the Estrogen regulated 24K protein and HSP28, is one of several small heat shock proteins (HSP) produced by all organisms studied. Hsp27 synthesis is induced by elevated temperature, as well as estrogen in hormone responsive cells. This protein is involved in stress resistance and actin organization. Interestingly, human HSP27 also shares greater than 50% homology with low molecular weight Drosophila HSP's and mammalian a-crystalline lens protein. Because of the estrogen responsive nature of Hsp27, this protein has been studied extensively in human estrogen responsive tissues such as cervix, endometrium and breast tissue. This work has led to the suggestion that Hsp27 may be a useful marker in classifying various hormone sensitive tumors.磷酸化热休克蛋白27抗体的质量标准:
■其它名称: | HSP27(Phospho-Ser82); Heat shock 27kDa protein 1; Heat shock 28kDa protein 1; Heat Shock P |
■交叉反应: | hu, rat, mo, MK |
■产品类型: | 一抗磷酸化抗体 |
■应用领域: | /肿瘤/免疫学/信号转导/转录调节因子 |
■蛋白分子: | predicted molecular weight: 27kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated Synthesised phosphopeptide derived from human HSP27 around the phosphorylation site of Ser82 |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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磷酸化热休克蛋白27抗体Anti-Phospho-HSP27 (Ser82)的相关产品目录:
1mg/1ml 磷酸化热休克蛋白27抗体 Anti-Phospho-HSP27 (Ser82) HSP27(Phospho-Ser82); Heat shock 27kDa protein 1; Heat shock 28kDa protein 1; Heat Shock P的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
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