胰岛素受体α抗体Anti-Insulin Receptor alphaCD 220; CD220; CD220 antigen; HHF 5; HHF5; INSR; IR; 4932439J01Rik; ALPHA SUBUNIT INSULIN
360TIYO.COM-上海田源公司

性能参数：

中文名称：胰岛素受体α抗体
英文名称：Anti-Insulin Receptor alpha
别名：CD 220; CD220; CD220 antigen; HHF 5; HHF5; INSR; IR; 4932439J01Rik; ALPHA SUBUNIT INSULIN
包装号：G320
产地：中国大陆/进口产品
商标/品牌：Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商：田源试剂 TR、新试剂 NR
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产品详细描述

产品介绍：The human insulin receptor is a heterotetrameric membrane glycoprotein consisting of disulfide linked subunits in a beta-alpha-alpha-beta configuration. The beta subunit （95 kDa） possesses a single transmembrane domain, whereas the alpha subunit （135 kDa） is completely extracellular. The insulin receptor exhibits receptor tyrosine kinase （RTK） activity. RTKs are single pass transmembrane receptors that possess intrinsic cytoplasmic enzymatic activity, catalyzing the transfer of the gamma phosphate of ATP to tyrosine residues in protein substrates. RTKs are essential components of signal transduction pathways that affect cell proliferation, differentiation, migration ａnd metabolism. Included in this large protein family are the insulin receptor ａnd the receptors for growth factors such as epidermal growth factor, fibroblast growth factor ａnd vascular endothelial growth factor. Receptor activation occurs through ligand binding, which facilitates receptor dimerization ａnd autophosphorylation of specific tyrosine residues in the cytoplasmic portion. The interaction of insulin with the alpha subunit of the insulin receptor activates the protein tyrosine kinase of the beta subunit, which then undergoes an autophosphorylation that increases its tyrosine kinase activity. Three adapter proteins, IRS1, IRS2 ａnd Shc, become phosphorylated on tyrosine residues following insulin receptor activation. These three phosphorylated proteins then interact with SH2 domain containing signaling proteins.

胰岛素受体α抗体的质量标准：

■其它名称：	CD 220; CD220; CD220 antigen; HHF 5; HHF5; INSR; IR; 4932439J01Rik; ALPHA SUBUNIT INSULIN
■交叉反应：	hu, mo, rat, dog, cow, pig, chk, shp, hrs, Rb
■产品类型：	一抗
■应用领域:	/心血管/细胞生物/神经生物学/信号转导/生长因子和激素/激酶和磷酸酶/糖尿病/新陈代谢
■蛋白分子：	predicted molecular weight: 152/253kDa
■浓度值：	1mg/1ml
■物理性状：	Lyophilized or Liquid
■免疫原：	KLH conjugated synthetic peptide derived from human Insulin Receptor alpha N-terminus
■亚型：	polyclonal
■纯化方法：	affinity purified by Protein A
■保存液：	0.01M PBS, pH 7.4 with 10 mg/ml BSA ａnd 0.1% Sodium azide
■应用技术：	//WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500（石蜡切片需做抗原修复）/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user.
■保存环境：	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

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质量投诉流程
1、向我们的客户服务部反应投诉原因及订单信息。
2、向我们发送投诉相关的证明材料。
3、田源时间进行质量投诉调查及处理调查结果。
4、田源将联系客户并提供质量投诉处理结果。

友情提醒：
部分进口产品投诉须按照进口产品要求的检测方法提供证据。
由于化学产品的特殊性，恕不接受以下投诉：
1、超过质量投诉期的进口产品投诉
2、非质量报告提及的指标投诉

胰岛素受体α抗体Anti-Insulin Receptor alpha的相关产品目录：







1mg/1ml 胰岛素受体α抗体 Anti-Insulin Receptor alpha CD 220; CD220; CD220 antigen; HHF 5; HHF5; INSR; IR; 4932439J01Rik; ALPHA SUBUNIT INSULIN 的来源为Rabbit，其相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗

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