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整合素α1抗体Anti-Integrin alpha 1/CD49aIntegrin alpha 1; CD49a; CD49a antigen; Itga 1; Itga1; Laminin and collagen receptor; Ver
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中文名称:整合素α1抗体
英文名称:Anti-Integrin alpha 1/CD49a
别名:Integrin alpha 1; CD49a; CD49a antigen; Itga 1; Itga1; Laminin and collagen receptor; Ver
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:Integrins are important extracellular matrix (ECM) receptor proteins located on cell surfaces. They are hetrodimers composed of an alpha and a beta transmembrane glycoprotein subunit. Around twenty two different integrins (different alpha/ beta subunit combinations) are found in nature. Integrins are generally present in high concentrations at the cell surface, but, unlike most other cell surface receptors, they bind ligands with very low affinity. Due to their weak individual binding, integrins need to cluster and bind in groups in order to effectively bind the ECM. Integrins bind many different ligands including laminin. Each integrin is made up of a large N terminal extracellular domain that binds the ECM ligand and a small C terminal cytoplasmic domain that mediates interaction with the actin cytoskeleton and signaling function. Alpha 1 integrin along with alpha 2, alpha L and alpha M has a unique inserted domain. Integrin alpha 1 is a receptor for laminin and collagen. The alpha1 subunit is also known as CD49a. CD49a associates with CD29 (beta 1 integrin), to form an alpha1 beta1 heterodimer, identified as the rat homologue to VLA1, which is involved in cellular adhesion to laminin and collagen.整合素α1抗体的质量标准:
■其它名称: | Integrin alpha 1; CD49a; CD49a antigen; Itga 1; Itga1; Laminin and collagen receptor; Ver |
■交叉反应: | hu, mo, rat, cow, hrs |
■产品类型: | 一抗 |
■应用领域: | /细胞生物/免疫学/信号转导/干细胞/细胞粘附分子 |
■蛋白分子: | predicted molecular weight: 130kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from human Integrin alpha 1 C-terminus |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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整合素α1抗体Anti-Integrin alpha 1/CD49a的相关产品目录:
1mg/1ml 整合素α1抗体 Anti-Integrin alpha 1/CD49a Integrin alpha 1; CD49a; CD49a antigen; Itga 1; Itga1; Laminin and collagen receptor; Ver的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
查询其它抗体目录请点击本公司化工仪器网链接:http://www.chem17.com/st233816/erlist_675408.html
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