白细胞介素6受体β抗体IL-6RβAnti-IL-6R Beta/CD130/gp130Interleukin-6 receptor subunit beta; IL-6R-beta; Interleukin-6 signal transducer; Membrane
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性能参数：

中文名称：白细胞介素6受体β抗体IL-6Rβ
英文名称：Anti-IL-6R Beta/CD130/gp130
别名：Interleukin-6 receptor subunit beta; IL-6R-beta; Interleukin-6 signal transducer; Membrane
包装号：G320
产地：中国大陆/进口产品
商标/品牌：Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商：田源试剂 TR、新试剂 NR
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产品详细描述

产品介绍：CD130 is a signal transducer shared by many cytokines, including interleukin 6 （IL6）, ciliary neurotrophic factor （CNTF）, leukemia inhibitory factor （LIF）, ａnd oncostatin M （OSM）. This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 ａnd encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor （IL6R） ａnd directly activate this protein. Knockout studies in mice suggested a critical role of the gene encoding this protein in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described. Signal-transducing molecule. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 ａnd BSF3 can utilize gp130 for initiating signal transmission. Binds to IL6/IL6R （alpha chain） complex, resulting in the formation of high-affinity IL6 binding sites, ａnd transduces the signal. Does not bind IL6. May have a role in embryonic development （By similarity）. The type I OSM receptor is capable of transducing OSM-specific signaling events. [SUBUNIT] Interacts with INPP5D/SHIP1. Forms heterodimers composed of LIPR ａnd IL6ST （type I OSM receptor）. Also forms heterodimers composed of OSMR ａnd IL6ST （type II OSM receptor）. Homodimer. The homodimer binds two molecules of herpes virus IL6. Component of a hexamer of two molecules each of IL6, IL6R ａnd IL6ST. Belongs to the type I cytokine receptor family. Type 2 subfamily.Subcellular Location : Secreted ａnd Cell membrane.Tissue Specificity : Found in all the tissues ａnd cell lines examined. Expression not restricted to IL6 responsive cells.

白细胞介素6受体β抗体IL-6Rβ的质量标准：

■其它名称：	Interleukin-6 receptor subunit beta; IL-6R-beta; Interleukin-6 signal transducer; Membrane
■交叉反应：	hu, mo, rat
■产品类型：	一抗
■应用领域:	/细胞生物/免疫学/信号转导/细胞膜受体
■蛋白分子：	predicted molecular weight: 101kDa
■浓度值：	1mg/1ml
■物理性状：	Lyophilized or Liquid
■免疫原：	KLH conjugated synthetic peptide derived from human IL6R beta C-terminus
■亚型：	polyclonal
■纯化方法：	affinity purified by Protein A
■保存液：	0.01M PBS, pH 7.4 with 10 mg/ml BSA ａnd 0.1% Sodium azide
■应用技术：	//WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500（石蜡切片需做抗原修复）/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user.
■保存环境：	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

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由于化学产品的特殊性，恕不接受以下投诉：
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白细胞介素6受体β抗体IL-6RβAnti-IL-6R Beta/CD130/gp130的相关产品目录：







1mg/1ml 白细胞介素6受体β抗体IL-6Rβ Anti-IL-6R Beta/CD130/gp130 Interleukin-6 receptor subunit beta; IL-6R-beta; Interleukin-6 signal transducer; Membrane的来源为Rabbit，其相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗

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