整合素αVβ5抗体Anti-Integrin Alpha V + Beta 5alpha 5; alpha polypeptide; CD49e; CD51; fibronectin receptor; FNRA; Integrin alpha V; Int
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性能参数：

中文名称：整合素αVβ5抗体
英文名称：Anti-Integrin Alpha V + Beta 5
别名：alpha 5; alpha polypeptide; CD49e; CD51; fibronectin receptor; FNRA; Integrin alpha V; Int
包装号：G320
产地：中国大陆/进口产品
商标/品牌：Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商：田源试剂 TR、新试剂 NR
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产品详细描述

产品介绍：Integrins are heterodimeric proteins made up of alpha ａnd beta subunits. At least 18 alpha ａnd 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion ａnd recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response ａnd metatastatic diffusion of tumour cells. ITAGV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain ａnd a beta chain. The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy ａnd light chains, that combine with multiple integrin beta chains to form different integrins. Among the known associating beta chains （beta chains 1,3,5,6, ａnd 8; ITGB1, ITGB3, ITGB5, ITGB6, ａnd ITGB8）, each can interact with extracellular matrix ligands; the alpha V beta 3 integrin, perhaps the most studied of these, is referred to as the Vitronectin receptor （VNR）. In addition to adhesion, many integrins are known to facilitate signal transduction.整合素αVβ3、αVβ5是特异性表达在血管内皮细胞表面的粘附因子，在介导内皮细胞和ECM相互接触中起作用。整合素（integrin）分布广泛，属于细胞黏附分子家族。经研究发现整合素可以调节细胞-细胞、细胞-细胞外基质（extracellular matrix，ECM〕间的黏附。整合素所介导的肿瘤细胞与ECM间的相互作用影响肿瘤的发生、增殖、侵袭和转移到其他组织的能力。

整合素αVβ5抗体的质量标准：

■其它名称：	alpha 5; alpha polypeptide; CD49e; CD51; fibronectin receptor; FNRA; Integrin alpha V; Int
■交叉反应：	hu, mo, rat
■产品类型：	一抗
■应用领域:	/细胞生物/干细胞/细胞粘附分子
■蛋白分子：	predicted molecular weight: 88/121kDa
■浓度值：	1mg/1ml
■物理性状：	Lyophilized or Liquid
■免疫原：	KLH conjugated synthetic peptide derived from human Integrin beta 5 ａnd Integrin alpha V C-terminus
■亚型：	polyclonal
■纯化方法：	affinity purified by Protein A
■保存液：	0.01M PBS, pH 7.4 with 10 mg/ml BSA ａnd 0.1% Sodium azide
■应用技术：	//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500（石蜡切片需做抗原修复）/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user.
■保存环境：	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

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由于化学产品的特殊性，恕不接受以下投诉：
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整合素αVβ5抗体Anti-Integrin Alpha V + Beta 5的相关产品目录：







1mg/1ml 整合素αVβ5抗体 Anti-Integrin Alpha V + Beta 5 alpha 5; alpha polypeptide; CD49e; CD51; fibronectin receptor; FNRA; Integrin alpha V; Int的来源为Rabbit，其相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗

查询其它抗体目录请点击本公司化工仪器网链接：http://www.chem17.com/st233816/erlist_675408.html

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