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白介素1受体1抗体Anti-IL-1R1/CD121a/IL1 Receptor IAntigen CD121a; CD121 antigen-like family member A; CD121a; CD121a antigen; D2S1473; IL 1;
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中文名称:白介素1受体1抗体
英文名称:Anti-IL-1R1/CD121a/IL1 Receptor I
别名:Antigen CD121a; CD121 antigen-like family member A; CD121a; CD121a antigen; D2S1473; IL 1;
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein is a receptor for interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA). It is an important mediator involved in many cytokine induced immune and inflammatory responses. This gene along with interleukin 1 receptor, type II(IL1R2), interleukin 1 receptor-like 2 (IL1RL2), and interleukin 1 receptor-like 1 (IL1RL1) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. [provided by RefSeq].Subcellular Location : Membrane; Single-pass type I membrane protein. Cell membrane (Probable). Secreted.Similarity : Belongs to the interleukin-1 receptor family.Contains 3 Ig-like C2-type (immunoglobulin-like) domains.Contains 1 TIR domain.Subunit : The interleukin-1 receptor complex is a heterodimer of IL1R1 and IL1RAP.IL-1RⅠ属于新的信号受体家族Toll信号转导通路蛋白,IL-1RⅠ在免疫和炎症反应的研究中占重要地位,是在很多感染 、炎症性致病机制中起决定性作用的细胞因子,几乎可作用于全身各种细胞,IL-1 与IL-1R1的结合可导致大量与免疫反应和炎症相关基因的表达 ,包括细胞因子、细胞因子受体、急性期反应物、生长因子、胞外基质、粘附分子等。IL-1R1/NF-κB信号通路是机体免疫反应中十分重要的组成部分。白介素1受体I型 Interleukin 1 receptor I(IL-1RI)白介素1受体1抗体的质量标准:
■其它名称: | Antigen CD121a; CD121 antigen-like family member A; CD121a; CD121a antigen; D2S1473; IL 1; |
■交叉反应: | hu, mo, rat |
■产品类型: | 一抗 |
■应用领域: | /免疫学/细胞表面分子 |
■蛋白分子: | predicted molecular weight: 63-75kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from human IL-1R1 C-terminus |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//Flow-Cyt=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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白介素1受体1抗体Anti-IL-1R1/CD121a/IL1 Receptor I的相关产品目录:
1mg/1ml 白介素1受体1抗体 Anti-IL-1R1/CD121a/IL1 Receptor I Antigen CD121a; CD121 antigen-like family member A; CD121a; CD121a antigen; D2S1473; IL 1;的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
查询其它抗体目录请点击本公司化工仪器网链接:http://www.chem17.com/st233816/erlist_675408.html
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