白介素-1受体相关激酶4抗体Anti-IRAK4IL-1 Receptor-associated Kinase 4; 8430405M07Rik; 9330209D03Rik; IPD1; IRAK4; NY-REN-64; R
360TIYO.COM-上海田源公司

性能参数：

中文名称：白介素-1受体相关激酶4抗体
英文名称：Anti-IRAK4
别名：IL-1 Receptor-associated Kinase 4; 8430405M07Rik; 9330209D03Rik; IPD1; IRAK4; NY-REN-64; R
包装号：G320
产地：中国大陆/进口产品
商标/品牌：Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商：田源试剂 TR、新试剂 NR
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产品详细描述

产品介绍：Interleukin 1 （IL1） ａnd lipopolysaccharide （LPS） induces cellular responses through IL1 receptor （IL1R） ａnd Toll like receptors （TLR）. IL1R associated kinases （IRAK, IRAK2, ａnd IRAKM） regulate the activation of NF-kB ａnd MAP kinase （MAPK） by IL1R/TLR. A novel member in the IRAK/Pelle family was recently identified ａnd designated IRAK4. Overexpression of IRAK4 activates NF-kB ａnd MAPK pathways. IRAK4 interacts with ａnd phosphorylates IRAK1. IRAK4 deficient animals are completely resistant to the challenge with LPS. Animals ａnd humans lacking IRAK4 are impaired in their responses to viral ａnd bacterial challenges. Members in IRAK/Pelle family play a central role in IL1R/TLR mediated inflammatory responses ａnd in innate immunity.Subcellular Location : Cytoplasm.Similarity : Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.Contains 1 death domain.Contains 1 protein kinase domain.Subunit : Associates with MYD88 ａnd IRAK2 to form a ternary complex called the Myddosome. Once phosphorylated, IRAK4 dissociates from the receptor complex ａnd then associates with the TNF receptor-associated factor 6 （TRAF6）, IRAK1, ａnd PELI1; this intermediate complex is required for subsequent NF-kappa-B activation. Interacts with IL1RL1.

白介素-1受体相关激酶4抗体的质量标准：

■其它名称：	IL-1 Receptor-associated Kinase 4; 8430405M07Rik; 9330209D03Rik; IPD1; IRAK4; NY-REN-64; R
■交叉反应：	hu, mo, rat, shp, pig, hrs, dog, cow
■产品类型：	一抗
■应用领域:	/细胞生物/免疫学/激酶和磷酸酶
■蛋白分子：	predicted molecular weight: 51kDa
■浓度值：	1mg/1ml
■物理性状：	Lyophilized or Liquid
■免疫原：	KLH conjugated synthetic peptide derived from human IRAK4
■亚型：	polyclonal
■纯化方法：	affinity purified by Protein A
■保存液：	0.01M PBS, pH 7.4 with 10 mg/ml BSA ａnd 0.1% Sodium azide
■应用技术：	//WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500（石蜡切片需做抗原修复）/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user.
■保存环境：	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

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质量投诉流程
1、向我们的客户服务部反应投诉原因及订单信息。
2、向我们发送投诉相关的证明材料。
3、田源时间进行质量投诉调查及处理调查结果。
4、田源将联系客户并提供质量投诉处理结果。

友情提醒：
部分进口产品投诉须按照进口产品要求的检测方法提供证据。
由于化学产品的特殊性，恕不接受以下投诉：
1、超过质量投诉期的进口产品投诉
2、非质量报告提及的指标投诉

白介素-1受体相关激酶4抗体Anti-IRAK4的相关产品目录：







1mg/1ml 白介素-1受体相关激酶4抗体 Anti-IRAK4 IL-1 Receptor-associated Kinase 4; 8430405M07Rik; 9330209D03Rik; IPD1; IRAK4; NY-REN-64; R的来源为Rabbit，其相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗

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