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磷酸化单丝氨酸蛋白激酶1/2抗体 田源一抗磷酸化抗体
点击次数:175发布时间:2012/8/7 15:57:02
更新日期:2013/6/7 11:30:38
所 在 地:其它
产品型号:Anti-Phospho-LIMK1(Thr508)/LIMK2(Thr505)
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详细内容
磷酸化单丝氨酸蛋白激酶1/2抗体Anti-Phospho-LIMK1(Thr508)/LIMK2(Thr505)LIMK1(Phospho-Thr508); EC 2.7.11.1; LIM domain kinase 1; LIM motif-containing protein kina
360TIYO.COM-上海田源公司
性能参数:
中文名称:磷酸化单丝氨酸蛋白激酶1/2抗体
英文名称:Anti-Phospho-LIMK1(Thr508)/LIMK2(Thr505)
别名:LIMK1(Phospho-Thr508); EC 2.7.11.1; LIM domain kinase 1; LIM motif-containing protein kina
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:LIMK1 is a protein kinase which regulates actin filament dynamics. Phosphorylates and inactivates the actin binding/depolymerizing factor cofilin, thereby stabilizing the actin cytoskeleton. LIMK1 may be involved in brain development; it is highly expressed in both adult and fetal nervous system. Detected ubiquitously throughout the different regions of adult brain, with highest levels in the cerebral cortex. Expressed to a lesser extent in heart and skeletal muscle.LIM激酶1(LIMkinase1,LIMK-1)是单丝氨酸蛋白激酶,LIMK-1的活化受多种机制调控,成为联系细胞外刺激与细胞骨架稳定性的枢纽,在多种基本的生物学过程中起重要作用。LIMK-1包含LIM和PDZ蛋白和蛋白相互作用区、P/S结构域、激酶结构域,在神经元中呈高表达。它的主要作用是使肌动蛋白解聚因子cofilin磷酸化和失活,从而导致肌动蛋白细胞骨架的改变。磷酸化单丝氨酸蛋白激酶1/2抗体的质量标准:
■其它名称: | LIMK1(Phospho-Thr508); EC 2.7.11.1; LIM domain kinase 1; LIM motif-containing protein kina |
■交叉反应: | hu, mo, rat, pig, hrs, cow, dog, chk, Rb |
■产品类型: | 一抗磷酸化抗体 |
■应用领域: | /肿瘤/免疫学/信号转导/转录调节因子/激酶和磷酸酶 |
■蛋白分子: | predicted molecular weight: 71kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthesised phosphopeptide derived from human LIMK1 around the phosphorylation site of Thr508 |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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磷酸化单丝氨酸蛋白激酶1/2抗体Anti-Phospho-LIMK1(Thr508)/LIMK2(Thr505)的相关产品目录:
1mg/1ml 磷酸化单丝氨酸蛋白激酶1/2抗体 Anti-Phospho-LIMK1(Thr508)/LIMK2(Thr505) LIMK1(Phospho-Thr508); EC 2.7.11.1; LIM domain kinase 1; LIM motif-containing protein kina的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
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