磷酸化氨基末端激酶1/2/3抗体Anti-phospho-JNK1/2/3（Thr183+Thr185）/p-JNKMAPK8（phospho T183/185）; p-JNK; c Jun N terminal kinase 1; C-JUN kinase 1; EC 2.7.11.24; J
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性能参数：

中文名称：磷酸化氨基末端激酶1/2/3抗体
英文名称：Anti-phospho-JNK1/2/3（Thr183+Thr185）/p-JNK
别名：MAPK8（phospho T183/185）; p-JNK; c Jun N terminal kinase 1; C-JUN kinase 1; EC 2.7.11.24; J
包装号：G320
产地：中国大陆/进口产品
商标/品牌：Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商：田源试剂 TR、新试剂 NR
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产品详细描述

产品介绍：JNK1 （MAPK8） is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, ａnd are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation ａnd development. This kinase is activated by various cell stimuli, ａnd targets specific transcription factors, ａnd thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha （TNF-alpha） is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrome c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis ａnd differentiation. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. JNK1 is activated by threonine ａnd tyrosine phosphorylation by either of two dual specificity kinases, MAP2K4 ａnd MAP2K7. The JNK pathway is critically involved in diabetes ａnd levels are abnormally elevated in obesity. The cell-permeable JNK inhibitory peptide may have promise as a therapeutic agent for diabetes.磷酸化抗体

磷酸化氨基末端激酶1/2/3抗体的质量标准：

■其它名称：	MAPK8（phospho T183/185）; p-JNK; c Jun N terminal kinase 1; C-JUN kinase 1; EC 2.7.11.24; J
■交叉反应：	hu, rat, mo
■产品类型：	一抗磷酸化抗体
■应用领域:	/肿瘤/免疫学/信号转导/转录调节因子
■蛋白分子：	predicted molecular weight: 42kDa
■浓度值：	1mg/1ml
■物理性状：	Lyophilized or Liquid
■免疫原：	KLH conjugated Synthesised phosphopeptide derived from human JNK1 around the phosphorylation site of Thr183/185
■亚型：	polyclonal
■纯化方法：	affinity purified by Protein A
■保存液：	0.01M PBS, pH 7.4 with 10 mg/ml BSA ａnd 0.1% Sodium azide
■应用技术：	//WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500（石蜡切片需做抗原修复）/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user.
■保存环境：	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

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磷酸化氨基末端激酶1/2/3抗体Anti-phospho-JNK1/2/3（Thr183+Thr185）/p-JNK的相关产品目录：







1mg/1ml 磷酸化氨基末端激酶1/2/3抗体 Anti-phospho-JNK1/2/3（Thr183+Thr185）/p-JNK MAPK8（phospho T183/185）; p-JNK; c Jun N terminal kinase 1; C-JUN kinase 1; EC 2.7.11.24; J的来源为Rabbit，其相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗

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