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氨基末端激酶2抗体Anti-JNK2Mapk9; C Jun kinase 2; C Jun N terminal kinase 2; JNK 2; JNK 55; JNK2 alpha; JNK2 beta; JN
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中文名称:氨基末端激酶2抗体
英文名称:Anti-JNK2
别名:Mapk9; C Jun kinase 2; C Jun N terminal kinase 2; JNK 2; JNK 55; JNK2 alpha; JNK2 beta; JN
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimuli. It is most closely related to MAPK8, both of which are involved in UV radiation induced apoptosis, thought to be related to the cytochrome c-mediated cell death pathway. This gene and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells. Studies of this gene's mouse counterpart suggest a key role in T-cell differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Sep 2008].Subcellular Location : Cytoplasm. Nucleus.Similarity : Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily. Contains 1 protein kinase domain.Subunit : Interacts with MECOM and DCLK2 (By similarity). Binds to at least four scaffolding proteins, MAPK8IP1/JIP-1, MAPK8IP2/JIP-2, MAPK8IP3/JIP-3/JSAP1 and SPAG9/MAPK8IP4/JIP-4. These proteins also bind other components of the JNK signaling pathway. Interacts with NFATC4. Interacts with ATF7; the interaction does not phosphorylate ATF7 but acts as a docking site for ATF7-associated partners such as JUN. Interacts with BCL10. Interacts with CTNNB1 and GSK3B.氨基末端激酶2抗体的质量标准:
■其它名称: | Mapk9; C Jun kinase 2; C Jun N terminal kinase 2; JNK 2; JNK 55; JNK2 alpha; JNK2 beta; JN |
■交叉反应: | hu, mo, rat, hrs, cow, pig, dog, Rb |
■产品类型: | 一抗 |
■应用领域: | /肿瘤/免疫学/信号转导/转录调节因子/糖尿病 |
■蛋白分子: | predicted molecular weight: 48kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from human JNK2 |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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氨基末端激酶2抗体Anti-JNK2的相关产品目录:
1mg/1ml 氨基末端激酶2抗体 Anti-JNK2 Mapk9; C Jun kinase 2; C Jun N terminal kinase 2; JNK 2; JNK 55; JNK2 alpha; JNK2 beta; JN的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
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