激肽释放酶3/舒血管素3抗体Anti-KLK3/Prostate Specific AntigenKallikrein 3; APS; Gamma seminoprotein; hK3; Kallikrein-3; Kallikrein related peptidase 3;
360TIYO.COM-上海田源公司

性能参数：

中文名称：激肽释放酶3/舒血管素3抗体
英文名称：Anti-KLK3/Prostate Specific Antigen
别名：Kallikrein 3; APS; Gamma seminoprotein; hK3; Kallikrein-3; Kallikrein related peptidase 3;
包装号：G320
产地：中国大陆/进口产品
商标/品牌：Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商：田源试剂 TR、新试剂 NR
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产品详细描述

产品介绍：Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis ａnd some have potential as novel cancer ａnd other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis ａnd monitoring of prostatic carcinoma. Alternate splicing of this gene generates two transcript variants encoding different isoforms. Additional transcript variants have been described, but it is unclear if these transcripts are normally expressed or if they are specific to benign or malignant tumors.Subcellular Location : Secreted.Tissue Specificity : ProstateSimilarity : Belongs to the peptidase S1 family. Kallikrein subfamily.Contains 1 peptidase S1 domain.Subunit : Forms heterodimer with SERPINA5.KLK3目前认为是前列腺癌很有意义的特异性标志物。激肽释放酶KLK是激肽系统的主要限速酶，它是一组存在于多数组织和体液中的丝氨酸蛋白酶，是一种肽链内切酶。KLK又称血管舒缓素，包括15个家族成员。在不同的组织中广泛表达,具有蛋白水解酶的活性。它特异性的在碳末端切割底物肽，可裂解激肽原释放具有活性的激肽，由激肽发挥对心血管系统及肾脏功能的调节作用。组织KLK是一个大的基因家族，主要分布在肺、肾、血管、脑、肾上腺组织，为一种中等大小的糖蛋白。

激肽释放酶3/舒血管素3抗体的质量标准：

■其它名称：	Kallikrein 3; APS; Gamma seminoprotein; hK3; Kallikrein-3; Kallikrein related peptidase 3;
■交叉反应：	hu
■产品类型：	一抗
■应用领域:	/肿瘤/细胞生物/信号转导/激酶和磷酸酶
■蛋白分子：	predicted molecular weight: 23kDa
■浓度值：	1mg/1ml
■物理性状：	Lyophilized or Liquid
■免疫原：	KLH conjugated synthetic peptide derived from human KLK3 C-terminus
■亚型：	polyclonal
■纯化方法：	affinity purified by Protein A
■保存液：	0.01M PBS, pH 7.4 with 10 mg/ml BSA ａnd 0.1% Sodium azide
■应用技术：	//WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500（石蜡切片需做抗原修复）/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user.
■保存环境：	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

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激肽释放酶3/舒血管素3抗体Anti-KLK3/Prostate Specific Antigen的相关产品目录：







1mg/1ml 激肽释放酶3/舒血管素3抗体 Anti-KLK3/Prostate Specific Antigen Kallikrein 3; APS; Gamma seminoprotein; hK3; Kallikrein-3; Kallikrein related peptidase 3;的来源为Rabbit，其相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗

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