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磷酸化丝裂原活化蛋白激酶激酶8抗体 田源一抗
点击次数:152发布时间:2012/8/7 16:03:39
更新日期:2013/6/7 11:29:29
所 在 地:其它
产品型号:Anti-Phospho-MAP3K8/Tpl2 (Ser400)
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详细内容
磷酸化丝裂原活化蛋白激酶激酶8抗体Anti-Phospho-MAP3K8/Tpl2 (Ser400)Cancer Osaka thyroid oncogene; COT proto oncogene serine/threonine protein kinase; c COT;
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性能参数:
中文名称:磷酸化丝裂原活化蛋白激酶激酶8抗体
英文名称:Anti-Phospho-MAP3K8/Tpl2 (Ser400)
别名:Cancer Osaka thyroid oncogene; COT proto oncogene serine/threonine protein kinase; c COT;
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:MAP3K8 is a member of the serine/threonine protein kinase family. This kinase can activate both the MAP kinase and JNK kinase pathways. MAP3K8 activates IkappaB kinases, and thus induces the nuclear production of NF-kappaB. It also promotes the production of TNF-alpha and IL-2 during T lymphocyte activation. There are two isoforms of MAP3K8: a 58 kDa and a 53 kDa form. The 58 kDa form is activated specifically during the S and G2/M phases of the cell cycle. The longer 58 kDa form undergoes phosphorylation on Ser residues mainly, and the shorter 53 kDa form undergoes phosphorylation on both Ser and Thr residues.Subcellular Location : Cytoplasm.Tissue Specificity : Expressed in several normal tissues and human tumor-derived cell lines.Similarity : Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. Contains 1 protein kinase domain.Subunit : Forms a ternary complex with NFKB1 and TNIP2.磷酸化丝裂原活化蛋白激酶激酶8抗体的质量标准:
■其它名称: | Cancer Osaka thyroid oncogene; COT proto oncogene serine/threonine protein kinase; c COT; |
■交叉反应: | hu, mo, rat, pig, dog, hrs, cow, chk, Rb |
■产品类型: | 一抗 |
■应用领域: | /肿瘤/细胞生物/免疫学/信号转导/转录调节因子/激酶和磷酸酶 |
■蛋白分子: | predicted molecular weight: 51kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated Synthesised phosphopeptide derived from human MAP3K8/Tpl2 around the phosphorylation site of Ser400 |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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磷酸化丝裂原活化蛋白激酶激酶8抗体Anti-Phospho-MAP3K8/Tpl2 (Ser400)的相关产品目录:
1mg/1ml 磷酸化丝裂原活化蛋白激酶激酶8抗体 Anti-Phospho-MAP3K8/Tpl2 (Ser400) Cancer Osaka thyroid oncogene; COT proto oncogene serine/threonine protein kinase; c COT; 的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
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