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磷酸化低密度脂蛋白受体相关蛋白6抗体 田源一抗磷酸化抗体
点击次数:156发布时间:2012/8/7 16:04:06
更新日期:2013/6/7 11:29:29
所 在 地:其它
产品型号:Anti-Phospho-LRP6 (Ser1490)
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详细内容
磷酸化低密度脂蛋白受体相关蛋白6抗体Anti-Phospho-LRP6 (Ser1490)ADCAD2; C030016K15Rik; Cd; FLJ90062; FLJ90421; Low density lipoprotein receptor related pr
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性能参数:
中文名称:磷酸化低密度脂蛋白受体相关蛋白6抗体
英文名称:Anti-Phospho-LRP6 (Ser1490)
别名:ADCAD2; C030016K15Rik; Cd; FLJ90062; FLJ90421; Low density lipoprotein receptor related pr
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:LRP6 is essential for the Wnt/beta catenin signaling pathway, probably by acting as a coreceptor together with Frizzled for Wnt. It is a specific, high-affinity receptor for DKK1 and DKK2, but not DKK3. The interaction with DKK1 blocks LRP6-mediated Wnt/beta catenin signaling via LRP6 removal via Kremen proteins-mediated endocytosis.Subcellular Location : Membrane; Single-pass type I membrane protein. Endoplasmic reticulum. Tissue Specificity : Widely co-expressed with LRP5 during embryogenesis and in adult tissues.Similarity : Belongs to the LDLR family. Contains 4 EGF-like domains. Contains 3 LDL-receptor class A domains. Contains 20 LDL-receptor class B repeats.Subunit : Homodimer; disulfide-linked.磷酸化低密度脂蛋白受体相关蛋白6抗体的质量标准:
■其它名称: | ADCAD2; C030016K15Rik; Cd; FLJ90062; FLJ90421; Low density lipoprotein receptor related pr |
■交叉反应: | hu, mo, rat, cow, dog, chk, hrs, pig |
■产品类型: | 一抗磷酸化抗体 |
■应用领域: | /肿瘤/免疫学/信号转导/转录调节因子/合成与降解 |
■蛋白分子: | predicted molecular weight: 179kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthesised phosphopeptide derived from human LRP6 around the phosphorylation site of Ser1490 |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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磷酸化低密度脂蛋白受体相关蛋白6抗体Anti-Phospho-LRP6 (Ser1490)的相关产品目录:
1mg/1ml 磷酸化低密度脂蛋白受体相关蛋白6抗体 Anti-Phospho-LRP6 (Ser1490) ADCAD2; C030016K15Rik; Cd; FLJ90062; FLJ90421; Low density lipoprotein receptor related pr的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
查询其它抗体目录请点击本公司化工仪器网链接:http://www.chem17.com/st233816/erlist_675408.html
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