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丙酮酸激酶-M2Anti-M2-PK (pyruvate Kinase M2)CTHBP; Cytosolic thyroid hormone binding protein; MGC3932; OIP 3; Oip3; OPA interacting pr
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性能参数:
中文名称:丙酮酸激酶-M2
英文名称:Anti-M2-PK (pyruvate Kinase M2)
别名:CTHBP; Cytosolic thyroid hormone binding protein; MGC3932; OIP 3; Oip3; OPA interacting pr
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:The protein encoded by this gene is a pyruvate kinase that catalyzes the production of phosphoenolpyruvate from pyruvate and ATP. This protein has been shown to interact with thyroid hormone, and thus may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported.丙酮酸激酶(PK)有L、R、M1、M2四种同功酶,均为四聚体。 L型主要分布于肝脏,R型存在于红细胞,在结构、免疫学和动力学上十分相似,由同一基因调控;M1存在于肌肉中,M2分布于除上述以外的其他组织(尤以肾脏*多)以及胎儿各组织。PK也是一种癌胚蛋白,在恶性肿瘤中,增高的都是M2型。丙酮酸激酶-M2的质量标准:
■其它名称: | CTHBP; Cytosolic thyroid hormone binding protein; MGC3932; OIP 3; Oip3; OPA interacting pr |
■交叉反应: | hu, mo, rat, Rb, cow, hrs, pig |
■产品类型: | 一抗 |
■应用领域: | /激酶和磷酸酶 |
■蛋白分子: | predicted molecular weight: 58kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from human M2-PK C-terminus |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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丙酮酸激酶-M2Anti-M2-PK (pyruvate Kinase M2)的相关产品目录:
1mg/1ml 丙酮酸激酶-M2 Anti-M2-PK (pyruvate Kinase M2) CTHBP; Cytosolic thyroid hormone binding protein; MGC3932; OIP 3; Oip3; OPA interacting pr的来源为Mouse,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
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