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上皮钙粘附分子抗体 田源一抗
点击次数:158发布时间:2012/8/8 20:24:20
更新日期:2013/6/7 10:38:11
所 在 地:其它
产品型号:Anti-E-cadherin/CD324
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详细内容
上皮钙粘附分子抗体Anti-E-cadherin/CD324Arc 1; Cadherin 1; E cadherin; cadherin 1 type 1 E-cadherin; Cadherin1; CAM 120/80; CD 234
360TIYO.COM-上海田源公司
性能参数:
中文名称:上皮钙粘附分子抗体
英文名称:Anti-E-cadherin/CD324
别名:Arc 1; Cadherin 1; E cadherin; cadherin 1 type 1 E-cadherin; Cadherin1; CAM 120/80; CD 234
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7. E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production.Subcellular Location : Cell junction. Cell membrane; Single-pass type I membrane protein.Tissue Specificity : Non-neural epithelial tissues.Similarity : Contains 5 cadherin domains.Subunit : Homodimer.细胞粘附蛋白(Call Adhesion Protein) E-chaherin是研究较多的同质粘附分子。E-cadherin的表达与恶性肿瘤的分化程度、侵袭力、转移负相关与预后正相关,E-cadherin的低表达和不稳定表达可促进转移的发生。近年来已成为肿瘤细胞侵袭和转移研究的热点。上皮钙粘附分子抗体的质量标准:
■其它名称: | Arc 1; Cadherin 1; E cadherin; cadherin 1 type 1 E-cadherin; Cadherin1; CAM 120/80; CD 234 |
■交叉反应: | hu, mo, rat, dog, cow, pig, hrs, chk |
■产品类型: | 一抗 |
■应用领域: | /肿瘤/细胞生物/免疫学/细胞粘附分子/细胞表面分子/上皮细胞 |
■蛋白分子: | predicted molecular weight: 20/80kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from human E-cadherin C-terminus |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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上皮钙粘附分子抗体Anti-E-cadherin/CD324的相关产品目录:
1mg/1ml 上皮钙粘附分子抗体 Anti-E-cadherin/CD324 Arc 1; Cadherin 1; E cadherin; cadherin 1 type 1 E-cadherin; Cadherin1; CAM 120/80; CD 234的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
查询其它抗体目录请点击本公司化工仪器网链接:http://www.chem17.com/st233816/erlist_675408.html
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