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核凋亡诱导因子蛋白1 田源一抗
点击次数:112发布时间:2012/8/8 20:25:50
更新日期:2013/6/7 10:37:42
所 在 地:其它
产品型号:Anti-NAIF1 protein
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详细内容
核凋亡诱导因子蛋白1Anti-NAIF1 proteinnuclear apoptosis inducing factor 1; CB12-327; 2310007O20Rik; 4933440H19Rik; bA379C10.2; C
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性能参数:
中文名称:核凋亡诱导因子蛋白1
英文名称:Anti-NAIF1 protein
别名:nuclear apoptosis inducing factor 1; CB12-327; 2310007O20Rik; 4933440H19Rik; bA379C10.2; C
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:NAIF protein 1 (nuclear apoptosis inducing factor 1; CB12-327; RP-379C10.2) belongs to the NAIF1 family. Apoptosis is a genetically determined cell suicidal pro gram that plays critical roles in many physiological and pathological processes. nuclear apoptosis-inducing factor 1 (NAIF1), overexpression of which induces apoptosis in cells. Human NAIF1 is located on chromosome 9q34.11 and encodes 327 amino acids with a homeodomain-like region and two nuclear localization signals at its N-terminal region. NAIF1 is conserved across diverse species, including human, mouse, crab-eating macaque, dog, chicken and frog, and shares no obvious homology to any known genes or proteins. Northern blot analysis revealed wide expression of NAIF1 mRNA throughout human tissues. NAIF1 was predominantly localized in the nucleus. Overexpression of NAIF1 inhibited cell growth and induced apoptosis. Furthermore, NAIF1 transfection caused both decreases in mitochondrial membrane potential and caspase-3 activation. In summary, NAIF1 is a nuclear protein that induces apoptosis when overexpressed.NAIF1 protein(CB12-327)是发现的大肠癌标志物他抑制NFκB,NFAT,AP-1活性,并诱导细胞调亡。核凋亡诱导因子蛋白1的质量标准:
■其它名称: | nuclear apoptosis inducing factor 1; CB12-327; 2310007O20Rik; 4933440H19Rik; bA379C10.2; C |
■交叉反应: | hu, mo, rat, hrs, chk, cow, dog |
■产品类型: | 一抗 |
■应用领域: | /染色质和核信号 |
■蛋白分子: | predicted molecular weight: 36kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from human NAIF1 N-terminus |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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核凋亡诱导因子蛋白1Anti-NAIF1 protein的相关产品目录:
1mg/1ml 核凋亡诱导因子蛋白1 Anti-NAIF1 protein nuclear apoptosis inducing factor 1; CB12-327; 2310007O20Rik; 4933440H19Rik; bA379C10.2; C的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
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