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错配修复蛋白6抗体Anti-MSH6DNA mismatch repair protein MSH6; G/T mismatch binding protein; GTBP; GTMBP; H
360TIYO.COM-上海田源公司
性能参数:
中文名称:错配修复蛋白6抗体
英文名称:Anti-MSH6
别名:DNA mismatch repair protein MSH6; G/T mismatch binding protein; GTBP; GTMBP; H
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:Defects in MSH6 are a cause of hereditary non-polyposis colorectal cancer (HNPCC) (Lynch syndrome). HNPCC is an autosomal, dominantly inherited disease associated with marked increase in cancer susceptibility. It is characterized by a familial predisposition to early onset colorectal carcinoma (crc) and extra-colonic cancers of the gastrointestinal, urological and female reproductive tracts. HNPCC is reported to be the most common form of inherited colorectal cancer in the western world. MSH6 is central to mismatch DNA repair.MSH6是DNA错配修复系统的基因组成。DNA错配修复系统由hMLH1,hMSH2,hPMS1,hPMS2,hMSH6和hMSH3等基因组成,这套系统的存在,可遗传物质的完整性和稳定性,避免遗传物质的突变产生,DNA复制的高保真度。错配修复蛋白6抗体的质量标准:
■其它名称: | DNA mismatch repair protein MSH6; G/T mismatch binding protein; GTBP; GTMBP; H |
■交叉反应: | hu, rat, mo |
■产品类型: | 一抗 |
■应用领域: | /肿瘤/免疫学/转录调节因子 |
■蛋白分子: | predicted molecular weight: 68kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from human MSH6 |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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错配修复蛋白6抗体Anti-MSH6的相关产品目录:
1mg/1ml 错配修复蛋白6抗体 Anti-MSH6 DNA mismatch repair protein MSH6; G/T mismatch binding protein; GTBP; GTMBP; H的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
查询其它抗体目录请点击本公司化工仪器网链接:http://www.chem17.com/st233816/erlist_675408.html
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