盐皮质激素受体抗体Anti-MCR/NR3C2/Mineralocorticoid receptorAldosterone receptor; MCR; MGC133092; MLR; MR; NR3 C2; NR3C2; NR3C2 protein; Nuclear recep
360TIYO.COM-上海田源公司

性能参数：

中文名称：盐皮质激素受体抗体
英文名称：Anti-MCR/NR3C2/Mineralocorticoid receptor
别名：Aldosterone receptor; MCR; MGC133092; MLR; MR; NR3 C2; NR3C2; NR3C2 protein; Nuclear recep
包装号：G320
产地：中国大陆/进口产品
商标/品牌：Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商：田源试剂 TR、新试剂 NR
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－

产品详细描述

产品介绍：Steroid receptors are ligand dependent, intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate hormone. Mineralocorticoids are a family of steroids, secreted by the adrenal cortex, necessary for the regulation of a number of metabolic processes including electrolyte regulation. These compounds exert their effect through their interaction with the mineralocorticoid receptor ａnd that complex＇s subsequent association with DNA. Given the function of mineralocorticoids, it is not surprising to find that the kidney is a primary target organ for mineralocorticoids ａnd that this organ has been shown to contain Mineralocorticoid Receptor.Subcellular Location : Cytoplasm. Nucleus. Endoplasmic reticulum membrane; Peripheral membrane protein. Note=Cytoplasmic ａnd nuclear in the absence of ligand; nuclear after ligand-binding. When bound to HSD11B2, it is found associated with the endoplasmic reticulum membrane.Tissue Specificity : Ubiquitous. Highly expressed in distal tubules, convoluted tubules ａnd cortical collecting duct in kidney, ａnd in sweat glands. Detected at lower levels in cardiomyocytes, in epidermis ａnd in colon enterocytes.Similarity : Belongs to the nuclear hormone receptor family. NR3 subfamily. Contains 1 nuclear receptor DNA-binding domain.Subunit : Heteromultimeric cytoplasmic complex with HSP90, HSP70, ａnd FKBP4, in the absence of ligand. After ligand binding, it translocates to the nucleus ａnd binds to DNA as a homodimer ａnd as a heterodimer with NR3C1. May interact with HSD11B2 in the absence of ligand. Binds the coactivators NCOA1, NCOA2, TIF1 ａnd NRIP1.Mineralocorticoid receptor属于类固醇/甲状腺/维生素A配体依赖的转录因子受体超家族，是调节机体水盐代谢的重要甾体激素，有重要的生理、病理功能。

盐皮质激素受体抗体的质量标准：

■其它名称：	Aldosterone receptor; MCR; MGC133092; MLR; MR; NR3 C2; NR3C2; NR3C2 protein; Nuclear recep
■交叉反应：	hu, mo, rat, pig, Rb, chk, cow, dog
■产品类型：	一抗
■应用领域:	/细胞生物/免疫学/转录调节因子
■蛋白分子：	predicted molecular weight: 170kDa
■浓度值：	1mg/1ml
■物理性状：	Lyophilized or Liquid
■免疫原：	KLH conjugated synthetic peptide derived from human Mineralocorticoid receptor C-terminus
■亚型：	polyclonal
■纯化方法：	affinity purified by Protein A
■保存液：	0.01M PBS, pH 7.4 with 10 mg/ml BSA ａnd 0.1% Sodium azide
■应用技术：	//WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500（石蜡切片需做抗原修复）/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user.
■保存环境：	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－

质量投诉流程
1、向我们的客户服务部反应投诉原因及订单信息。
2、向我们发送投诉相关的证明材料。
3、田源时间进行质量投诉调查及处理调查结果。
4、田源将联系客户并提供质量投诉处理结果。

友情提醒：
部分进口产品投诉须按照进口产品要求的检测方法提供证据。
由于化学产品的特殊性，恕不接受以下投诉：
1、超过质量投诉期的进口产品投诉
2、非质量报告提及的指标投诉

盐皮质激素受体抗体Anti-MCR/NR3C2/Mineralocorticoid receptor的相关产品目录：







1mg/1ml 盐皮质激素受体抗体 Anti-MCR/NR3C2/Mineralocorticoid receptor Aldosterone receptor; MCR; MGC133092; MLR; MR; NR3 C2; NR3C2; NR3C2 protein; Nuclear recep的来源为Rabbit，其相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗

查询其它抗体目录请点击本公司化工仪器网链接：http://www.chem17.com/st233816/erlist_675408.html

上海田源专业销售盐皮质激素受体抗体 Anti-MCR/NR3C2/Mineralocorticoid receptor，了解更多请点击查询！