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丝裂原活化蛋白激酶8相互作用蛋白1 田源一抗
点击次数:141发布时间:2012/8/8 20:29:23
更新日期:2013/6/7 10:37:16
所 在 地:其它
产品型号:Anti-JIP1/MAPK8IP1
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详细内容
丝裂原活化蛋白激酶8相互作用蛋白1Anti-JIP1/MAPK8IP1C jun amino terminal kinase interacting protein 1; IB 1; IB1; Islet brain 1; J
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性能参数:
中文名称:丝裂原活化蛋白激酶8相互作用蛋白1
英文名称:Anti-JIP1/MAPK8IP1
别名:C jun amino terminal kinase interacting protein 1; IB 1; IB1; Islet brain 1; J
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module and is required for JNK activation in response to excitotoxic stress. Cytoplasmic JIP1 causes inhibition of JNK-regulated activity by retaining JNK in the cytoplasm and inhibiting JNK phosphorylation of c-Jun. It may also participate in ApoER2-specific reelin signaling and directly, or indirectly, regulates GLUT2 gene expression and beta-cell function. It appears to have a role in cell signaling in mature and developing nerve terminals and may function as a regulator of vesicle transport, through interactions with the JNK-signaling components and motor proteins. It functions as an anti-apoptotic protein whose level seems to influence the beta-cell death or survival response.丝裂原活化蛋白激酶8相互作用蛋白1的质量标准:
■其它名称: | C jun amino terminal kinase interacting protein 1; IB 1; IB1; Islet brain 1; J |
■交叉反应: | hu, mo, rat |
■产品类型: | 一抗 |
■应用领域: | /肿瘤/信号转导/激酶和磷酸酶/细胞骨架 |
■蛋白分子: | predicted molecular weight: 78kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from human JIP1/MAPK8IP1 |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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丝裂原活化蛋白激酶8相互作用蛋白1Anti-JIP1/MAPK8IP1的相关产品目录:
1mg/1ml 丝裂原活化蛋白激酶8相互作用蛋白1 Anti-JIP1/MAPK8IP1 C jun amino terminal kinase interacting protein 1; IB 1; IB1; Islet brain 1; J的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
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