磷酸化丝裂原活化蛋白激酶激酶8抗体Anti-Phospho-MAP3K8/Tpl2 （Thr290）Cancer Osaka thyroid oncogene; COT proto oncogene serine/threonine protein kinase; c COT;
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性能参数：

中文名称：磷酸化丝裂原活化蛋白激酶激酶8抗体
英文名称：Anti-Phospho-MAP3K8/Tpl2 （Thr290）
别名：Cancer Osaka thyroid oncogene; COT proto oncogene serine/threonine protein kinase; c COT;
包装号：G320
产地：中国大陆/进口产品
商标/品牌：Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商：田源试剂 TR、新试剂 NR
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产品详细描述

产品介绍：This gene is an oncogene that encodes a member of the serine/threonine protein kinase family. The encoded protein localizes to the cytoplasm ａnd can activate both the MAP kinase ａnd JNK kinase pathways. This protein was shown to activate IkappaB kinases, ａnd thus induce the nuclear production of NF-kappaB. This protein was also found to promote the production of TNF-alpha ａnd IL-2 during T lymphocyte activation. This gene may also utilize a downstream in-frame translation start codon, ａnd thus produce an isoform containing a shorter N-terminus. The shorter isoform has been shown to display weaker transforming activity. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2011].Subcellular Location : Cytoplasm.Tissue Specificity : Expressed in several normal tissues ａnd human tumor-derived cell lines.Similarity : Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. Contains 1 protein kinase domain.Subunit : Forms a ternary complex with NFKB1 ａnd TNIP2.

磷酸化丝裂原活化蛋白激酶激酶8抗体的质量标准：

■其它名称：	Cancer Osaka thyroid oncogene; COT proto oncogene serine/threonine protein kinase; c COT;
■交叉反应：	hu, mo, rat, cow, chk, dog, hrs, pig, Rb
■产品类型：	一抗磷酸化抗体
■应用领域:	/肿瘤/免疫学/信号转导/转录调节因子/激酶和磷酸酶
■蛋白分子：	predicted molecular weight: 51kDa
■浓度值：	1mg/1ml
■物理性状：	Lyophilized or Liquid
■免疫原：	KLH conjugated Synthesised phosphopeptide derived from human MAP3K8/Tpl2 around the phosphorylation site of Thr290
■亚型：	polyclonal
■纯化方法：	affinity purified by Protein A
■保存液：	0.01M PBS, pH 7.4 with 10 mg/ml BSA ａnd 0.1% Sodium azide
■应用技术：	//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500（石蜡切片需做抗原修复）/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user.
■保存环境：	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

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磷酸化丝裂原活化蛋白激酶激酶8抗体Anti-Phospho-MAP3K8/Tpl2 （Thr290）的相关产品目录：







1mg/1ml 磷酸化丝裂原活化蛋白激酶激酶8抗体 Anti-Phospho-MAP3K8/Tpl2 （Thr290） Cancer Osaka thyroid oncogene; COT proto oncogene serine/threonine protein kinase; c COT; 的来源为Rabbit，其相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗

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