产品展示
金属肽链内切酶抗体 田源一抗
点击次数:315发布时间:2012/8/8 20:32:34
更新日期:2013/6/7 10:36:23
所 在 地:其它
产品型号:Anti-CD10/MME/Neprilysin
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详细内容
金属肽链内切酶抗体Anti-CD10/MME/NeprilysinNeprilysin; Membrane metallo-endopeptidase; MME; CALLA; Neutral endopeptidase 24.11; Neutr
360TIYO.COM-上海田源公司
性能参数:
中文名称:金属肽链内切酶抗体
英文名称:Anti-CD10/MME/Neprilysin
别名:Neprilysin; Membrane metallo-endopeptidase; MME; CALLA; Neutral endopeptidase 24.11; Neutr
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than45 kb. The 5' untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts. The coding region is not affected by alternative splicing.CD10即共同型急性淋巴细胞白血病抗原,是II型跨膜糖蛋白.CD10表达于早期B淋巴细胞,某些粒性白细胞,骨髓基质细胞,部分上皮组织及其起源的肿瘤细胞中也有表达.主要应用于某些恶性淋巴瘤和白血病的分型.CD10是一种94kD的锌依赖性细胞膜金属结合蛋白,参与细胞神经肽和激素肽的后分泌过程。它广泛地分布于肾、肝、小肠、胎盘、脉络膜丛、脑腺、腺皮质和白细胞,CD10是生发中心细胞及所致淋巴瘤的标志物。金属肽链内切酶抗体的质量标准:
■其它名称: | Neprilysin; Membrane metallo-endopeptidase; MME; CALLA; Neutral endopeptidase 24.11; Neutr |
■交叉反应: | hu, mo, rat |
■产品类型: | 一抗 |
■应用领域: | /细胞粘附分子/细胞骨架 |
■蛋白分子: | predicted molecular weight: 85kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from human NEP/MME |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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金属肽链内切酶抗体Anti-CD10/MME/Neprilysin的相关产品目录:
1mg/1ml 金属肽链内切酶抗体 Anti-CD10/MME/Neprilysin Neprilysin; Membrane metallo-endopeptidase; MME; CALLA; Neutral endopeptidase 24.11; Neutr的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
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