神经突触前膜胞内蛋白18抗体Anti-STXBP1/Munc18Munc 18 1; Munc 18a; NSec1; p67; Rb sec1; STXBP1; Syntaxin binding protein 1; Unc 18 homol
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性能参数：

中文名称：神经突触前膜胞内蛋白18抗体
英文名称：Anti-STXBP1/Munc18
别名：Munc 18 1; Munc 18a; NSec1; p67; Rb sec1; STXBP1; Syntaxin binding protein 1; Unc 18 homol
包装号：G320
产地：中国大陆/进口产品
商标/品牌：Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商：田源试剂 TR、新试剂 NR
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产品详细描述

产品介绍：Munc18 may participate in the regulation of synaptic vesicle docking ａnd fusion, possibly through interaction with GTP binding proteins. It is essential for neurotransmission ａnd binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Munc18 can interact with syntaxins 1, 2, ａnd 3 but not syntaxin 4. It may play a role in determining the specificity of intracellular fusion reactions.Mutations in Munc18 can result in accumulations of acetylcholine ａnd paralytic phenotype suggestive of a neurotransmitter release defect. Two Munc18 isoforms have recently been identified. Munc18-1 has been shown to be primarily expressed in brain, while Munc18-2 is expressed in most tissues.Subcellular Location : Cytoplasm. Membrane; Peripheral membrane protein.Tissue Specificity : Brain ａnd spinal cord. Highly enriched in axons.Similarity : Belongs to the STXBP/unc-18/SEC1 family.Subunit : Binds SYTL4. Interacts with STX1A.

神经突触前膜胞内蛋白18抗体的质量标准：

■其它名称：	Munc 18 1; Munc 18a; NSec1; p67; Rb sec1; STXBP1; Syntaxin binding protein 1; Unc 18 homol
■交叉反应：	hu, mo, rat, dog, hrs, pig, chk
■产品类型：	一抗
■应用领域:	/肿瘤/细胞生物/免疫学/神经生物学
■蛋白分子：	predicted molecular weight: 65kDa
■浓度值：	1mg/1ml
■物理性状：	Lyophilized or Liquid
■免疫原：	KLH conjugated synthetic peptide derived from human Munc18 （2-45aa）
■亚型：	polyclonal
■纯化方法：	affinity purified by Protein A
■保存液：	0.01M PBS, pH 7.4 with 10 mg/ml BSA ａnd 0.1% Sodium azide
■应用技术：	//WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500（石蜡切片需做抗原修复）/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user.
■保存环境：	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

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部分进口产品投诉须按照进口产品要求的检测方法提供证据。
由于化学产品的特殊性，恕不接受以下投诉：
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神经突触前膜胞内蛋白18抗体Anti-STXBP1/Munc18的相关产品目录：







1mg/1ml 神经突触前膜胞内蛋白18抗体 Anti-STXBP1/Munc18 Munc 18 1; Munc 18a; NSec1; p67; Rb sec1; STXBP1; Syntaxin binding protein 1; Unc 18 homol的来源为Rabbit，其相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗

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