产品展示
黑皮质素-1受体抗体 田源一抗
点击次数:133发布时间:2012/8/8 20:34:06
更新日期:2013/6/7 10:34:38
所 在 地:其它
产品型号:Anti-MC-1R
优质供应
详细内容
黑皮质素-1受体抗体Anti-MC-1RMC1R; Melanocortin 1 receptor; Melanocortin receptor 1; MSHR.
360TIYO.COM-上海田源公司
性能参数:
中文名称:黑皮质素-1受体抗体
英文名称:Anti-MC-1R
别名:MC1R; Melanocortin 1 receptor; Melanocortin receptor 1; MSHR.
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:This intronless gene encodes the receptor protein for melanocyte -stimulating hormone (MSH). The encoded protein, a seven pass transmembrane G protein coupled receptor, controls melanogenesis. Two types of melanin exist: red pheomelanin and black eumelanin. Gene mutations that lead to a loss in function are associated with increased pheomelanin production, which leads to lighter skin and hair color. Eumelanin is photoprotective but pheomelanin may contribute to UV-induced skin damage by generating free radicals upon UV radiation. Binding of MSH to its receptor activates the receptor and stimulates eumelanin synthesis. This receptor is a major determining factor in sun sensitivity and is a genetic risk factor for melanoma and non-melanoma skin cancer. Over30 variant alleles have been identified which correlate with skin and hair color, providing evidence that this gene is an important component in determining normal human pigment variation.Subcellular Location : Cell membrane; Multi-pass membrane protein.Tissue Specificity : Melanocytes and corticoadrenal tissue.Similarity : Belongs to the G-protein coupled receptor 1 family.类固醇受体(Steroid Receptors)黑皮质素-1受体抗体的质量标准:
■其它名称: | MC1R; Melanocortin 1 receptor; Melanocortin receptor 1; MSHR. |
■交叉反应: | hu, mo, rat |
■产品类型: | 一抗 |
■应用领域: | /生长因子和激素 |
■蛋白分子: | predicted molecular weight: 35kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from human MC-1R C-terminus |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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黑皮质素-1受体抗体Anti-MC-1R的相关产品目录:
1mg/1ml 黑皮质素-1受体抗体 Anti-MC-1R MC1R; Melanocortin 1 receptor; Melanocortin receptor 1; MSHR. 的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
查询其它抗体目录请点击本公司化工仪器网链接:http://www.chem17.com/st233816/erlist_675408.html
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