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磷酸化P27抗体/周期素依赖激酶抑制剂抗体 田源一抗磷酸化抗体

点击次数:125发布时间:2012/8/9 11:50:45

磷酸化P27抗体/周期素依赖激酶抑制剂抗体 田源一抗磷酸化抗体

更新日期:2013/6/7 10:32:42

所 在 地:其它

产品型号:Anti-phospho-CDKN1B/P27kip1 (Ser178)

简单介绍:磷酸化P27抗体/周期素依赖激酶抑制剂抗体价格查询,磷酸化P27抗体/周期素依赖激酶抑制剂抗体现货供应!别名:Anti-phospho-CDKN1B/P27kip1 (Ser178) cyclin-dependent kinase inhibitor 1B; p27, kip1; Cdkn1b; Cyclin- dependent kinase inhibito。专业抗体产品生产和代理销售商,田源商标!

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详细内容

磷酸化P27抗体/周期素依赖激酶抑制剂抗体Anti-phospho-CDKN1B/P27kip1 (Ser178)cyclin-dependent kinase inhibitor 1B; p27, kip1; Cdkn1b; Cyclin- dependent kinase inhibito
360TIYO.COM-上海田源公司


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中文名称:磷酸化P27抗体/周期素依赖激酶抑制剂抗体
英文名称:Anti-phospho-CDKN1B/P27kip1 (Ser178)
别名:cyclin-dependent kinase inhibitor 1B; p27, kip1; Cdkn1b; Cyclin- dependent kinase inhibito
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述

产品介绍:Cell cycle progression is regulated by cyclins and their cognate Cdks. p27 KIP 1 is a cell cycle regulatory mitotic inhibitor of cdk activity. p27 KIP 1 is a candidate tumor suppressor gene, and has been proposed to function as a possible mediator of TGF beta induced G1 arrest. p27 KIP 1 is up regulated in response to antimitogenic stimuli. The increased protein expression of p27 results in cellular arrest by binding to cyclin/Cdk complexes such as cyclin D1/Cdk4. p27 Kip1 is regulated by phosphorylation on serine 10 (S10) and threonine 187 (T187). Phosphorylation by CDK2 on T187 results in ubiquitylation and degradation of p27 Kip 1; while phosphorylation by hKIS on S10 signals the nuclear export to the cytoplasm.P27蛋白是一种新发现的周期素依赖激酶抑制剂,属于细胞周期的负性调控因子。P27基因及其产物的异常表达可能与某些肿瘤的发生、发展有着密切的关系。P27蛋白对细胞周期的调控及在肿瘤中发挥着很重要的作用。

磷酸化P27抗体/周期素依赖激酶抑制剂抗体的质量标准:
■其它名称:cyclin-dependent kinase inhibitor 1B; p27, kip1; Cdkn1b; Cyclin- dependent kinase inhibito
■交叉反应:hu, mo, rat
■产品类型:一抗磷酸化抗体
■应用领域:/免疫学/细胞周期蛋白/激酶和磷酸酶
■蛋白分子:predicted molecular weight: 27kDa
■浓度值:1mg/1ml
■物理性状:Lyophilized or Liquid
■免疫原:KLH conjugated Synthesised phosphopeptide derived from human CDKN1B around the phosphorylation site of Ser178
■亚型:polyclonal
■纯化方法:affinity purified by Protein A
■保存液:0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
■应用技术://WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user.
■保存环境:Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

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磷酸化P27抗体/周期素依赖激酶抑制剂抗体Anti-phospho-CDKN1B/P27kip1 (Ser178)的相关产品目录:







1mg/1ml 磷酸化P27抗体/周期素依赖激酶抑制剂抗体 Anti-phospho-CDKN1B/P27kip1 (Ser178) cyclin-dependent kinase inhibitor 1B; p27, kip1; Cdkn1b; Cyclin- dependent kinase inhibito的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗

查询其它抗体目录请点击本公司化工仪器网链接:http://www.chem17.com/st233816/erlist_675408.html

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