P73肿瘤抑制基因抗体Anti-P73 proteinp53 like transcription factor; p53 Related Protein; p73; TP 73; TP73; Tumor Protein p73.
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性能参数：

中文名称：P73肿瘤抑制基因抗体
英文名称：Anti-P73 protein
别名：p53 like transcription factor; p53 Related Protein; p73; TP 73; TP73; Tumor Protein p73.
包装号：G320
产地：中国大陆/进口产品
商标/品牌：Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商：田源试剂 TR、新试剂 NR
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产品详细描述

产品介绍：P73 protein is a structural ａnd functional homologue of p53, a tumor suppressor gene. In this study, The p73 protein, p19ras, by the yeast two-hybrid screening method. Alternative splicing of the proto-oncogene H-ras pre-mRNA has led to two distinct transcripts, Ras proteins are known to be small membrane-localized guanine nucleotide-binding proteins. However, unlike other Ras proteins, p19ras is localized in the nucleus ａnd the cytosol ａnd its interaction with P73 protein occurred exclusively in the nucleus. Oncogenic MDM2 （mouse double minutes 2） is a known repressor of p73 transcriptional activity. In this study, when p19ras was bound to MDM2, it further inhibited the association of MDM2 to the p73 protein. Therefore, this study presents a novel pathway of Ras signaling that occurs in the nucleus, involving p19ras ａnd p73.P73是p53基因家族的个成员p53基因是一个经典的抑癌基因,与p53在结构和功能方面具有很高的相似性。

P73肿瘤抑制基因抗体的质量标准：

■其它名称：	p53 like transcription factor; p53 Related Protein; p73; TP 73; TP73; Tumor Protein p73.
■交叉反应：	mo, rat, hu
■产品类型：	一抗
■应用领域:	/肿瘤/细胞生物/免疫学/信号转导/细胞凋亡/转录调节因子
■蛋白分子：	predicted molecular weight: 70kDa
■浓度值：	1mg/1ml
■物理性状：	Lyophilized or Liquid
■免疫原：	KLH conjugated synthetic peptide derived from mouse P73 protein C-terminus
■亚型：	polyclonal
■纯化方法：	affinity purified by Protein A
■保存液：	0.01M PBS, pH 7.4 with 10 mg/ml BSA ａnd 0.1% Sodium azide
■应用技术：	//WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500（石蜡切片需做抗原修复）/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user.
■保存环境：	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

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P73肿瘤抑制基因抗体Anti-P73 protein的相关产品目录：







1mg/1ml P73肿瘤抑制基因抗体 Anti-P73 protein p53 like transcription factor; p53 Related Protein; p73; TP 73; TP73; Tumor Protein p73.的来源为Rabbit，其相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗

查询其它抗体目录请点击本公司化工仪器网链接：http://www.chem17.com/st233816/erlist_675408.html

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