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谷氨酸受体2D抗体 田源一抗
点击次数:112发布时间:2012/8/9 11:56:11
更新日期:2013/6/6 11:14:09
所 在 地:其它
产品型号:Anti-NR2D/NMDAR2D
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详细内容
谷氨酸受体2D抗体Anti-NR2D/NMDAR2DGlutamate [NMDA] receptor subunit epsilon 4; Grin2d; N-methyl D-aspartate receptor subtype
360TIYO.COM-上海田源公司
性能参数:
中文名称:谷氨酸受体2D抗体
英文名称:Anti-NR2D/NMDAR2D
别名:Glutamate [NMDA] receptor subunit epsilon 4; Grin2d; N-methyl D-aspartate receptor subtype
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:NR2D is a NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. NR2D is expressed in the brain; it is detected in embryonic stages, peaks at postnatal day 7, and decreases thereafter to adult levels.[FUNCTION] NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. [SUBUNIT] Forms heteromeric channel of a zeta subunit (GRIN1), a epsilon subunit (GRIN2A, GRIN2B, GRIN2C or GRIN2D) and a third subunit (GRIN3A or GRIN3B). Interacts with PDZ domains of INADL and DLG4. [SUBCELLULAR LOCATION] Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. [TISSUE SPECIFICITY] Expressed in brain, mainly in the subcortical region. [SIMILARITY] Belongs to the glutamate-gated ion channel.Subcellular Location : Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.Similarity : Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR2D/GRIN2D subfamily.Subunit : Interacts with PDZ domains of INADL and DLG4 (By similarity). Forms heteromeric channel of a zeta subunit (GRIN1), a epsilon subunit (GRIN2A, GRIN2B, GRIN2C or GRIN2D) and a third subunit (GRIN3A or GRIN3B).谷氨酸受体2D(NR2D 又称作Glutamate Receptor NMDAR2D;Glutamate receptor;N-Methyl-d-Asprtate receptor-2D)是脊椎动物中枢神经系统兴奋型神经传递的主要介质。在突触可塑性极大脑学习及记忆功能方面起关键作用。谷氨酸受体2D抗体的质量标准:
■其它名称: | Glutamate [NMDA] receptor subunit epsilon 4; Grin2d; N-methyl D-aspartate receptor subtype |
■交叉反应: | hu, mo, rat, cow, dog, pig |
■产品类型: | 一抗 |
■应用领域: | /神经生物学 |
■蛋白分子: | predicted molecular weight: 143kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from human NR2D N-terminus |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//Flow-Cyt=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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谷氨酸受体2D抗体Anti-NR2D/NMDAR2D的相关产品目录:
1mg/1ml 谷氨酸受体2D抗体 Anti-NR2D/NMDAR2D Glutamate [NMDA] receptor subunit epsilon 4; Grin2d; N-methyl D-aspartate receptor subtype的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
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