磷酸化细胞核因子p50/k基因结合核因子抗体Anti-Phospho-NFKB1（Ser338）NFKB1（phospho S337）; NF kappa B; NFKB 1; NFKB p105; NFKB p50; NFKB1; Nuclear factor kappa
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性能参数：

中文名称：磷酸化细胞核因子p50/k基因结合核因子抗体
英文名称：Anti-Phospho-NFKB1（Ser338）
别名：NFKB1（phospho S337）; NF kappa B; NFKB 1; NFKB p105; NFKB p50; NFKB1; Nuclear factor kappa
包装号：G320
产地：中国大陆/进口产品
商标/品牌：Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商：田源试剂 TR、新试剂 NR
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产品详细描述

产品介绍：This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor ａnd the 50 kD protein is a DNA binding subunit of the NF-kappa-B （NFKB） protein complex. NFKB is a transcription regulator that is activated by various intra- ａnd extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, ａnd bacterial or viral products. Activated NFKB translocates into the nucleus ａnd stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. SUBUNIT: Active NF-kappa-B is a heterodimer of an about 50 kDa DNA-binding subunit ａnd the weak DNA-binding subunit p65. Two heterodimers might form a labile tetramer. Also interacts with MAP3K8. NF-kappa-B p50 subunit interacts with NCOA3 coactivator, which may coactivate NF-kappa-B dependent expression via its histone acetyltransferase activity. Interacts with DSIPI; this interaction prevents nuclear translocation ａnd DNA-binding. Interacts with SPAG9 ａnd UNC5CL.Subcellular Location : Nucleus. Cytoplasm. Note=Nuclear, but also found in the cytoplasm in an inactive form complexed to an inhibitor （I-kappa-B）.Similarity : Contains 7 ANK repeats. Contains 1 death domain. Contains 1 RHD （Rel-like） domain.Subunit : Component of the NF-kappa-B p65-p50 complex. Component of the NF-kappa-B p65-p50 complex. Homodimer; component of the NF-kappa-B p50-p50 complex. Component of the NF-kappa-B p105-p50 complex. Component of the NF-kappa-B p50-c-Rel complex. Component of a complex consisting of the NF-kappa-B p50-p50 homodimer ａnd BCL3. Also interacts with MAP3K8. NF-kappa-B p50 subunit interacts with NCOA3 coactivator, which may coactivate NF-kappa-B dependent expression via its histone acetyltransferase activity. Interacts with DSIPI; this interaction prevents nuclear translocation ａnd DNA-binding. Interacts with SPAG9 ａnd UNC5CL. NFKB1/p105 interacts with CFLAR; the interaction inhibits p105 processing into p50. NFKB1/p105 forms a ternary complex with MAP3K8 ａnd TNIP2. Interacts with GSK3B; the interaction prevents processing of p105 to p50. NFKB1/p50 interacts with NFKBIE. NFKB1/p50 interacts with NFKBIZ. Nuclear factor NF-kappa-B p50 subunit interacts with NFKBID （By similarity）. Directly interacts with MEN1. Interacts with HIF1AN.

磷酸化细胞核因子p50/k基因结合核因子抗体的质量标准：

■其它名称：	NFKB1（phospho S337）; NF kappa B; NFKB 1; NFKB p105; NFKB p50; NFKB1; Nuclear factor kappa
■交叉反应：	hu, pig, cow
■产品类型：	一抗磷酸化抗体
■应用领域:	/肿瘤/免疫学/信号转导/转录调节因子/激酶和磷酸酶
■蛋白分子：	predicted molecular weight: 48/105kDa
■浓度值：	1mg/1ml
■物理性状：	Lyophilized or Liquid
■免疫原：	KLH conjugated Synthesised phosphopeptide derived from human NF KappaB p105 around the phosphorylation site of Ser337
■亚型：	polyclonal
■纯化方法：	affinity purified by Protein A
■保存液：	0.01M PBS, pH 7.4 with 10 mg/ml BSA ａnd 0.1% Sodium azide
■应用技术：	//WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500（石蜡切片需做抗原修复）/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user.
■保存环境：	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

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磷酸化细胞核因子p50/k基因结合核因子抗体Anti-Phospho-NFKB1（Ser338）的相关产品目录：







1mg/1ml 磷酸化细胞核因子p50/k基因结合核因子抗体 Anti-Phospho-NFKB1（Ser338） NFKB1（phospho S337）; NF kappa B; NFKB 1; NFKB p105; NFKB p50; NFKB1; Nuclear factor kappa 的来源为Rabbit，其相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗

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