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丘脑分泌素受体抗体(食欲素受体) 田源一抗
点击次数:158发布时间:2012/8/9 12:00:39
更新日期:2013/6/6 11:12:55
所 在 地:其它
产品型号:Anti-CD200R/Orexin receptor
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详细内容
丘脑分泌素受体抗体(食欲素受体)Anti-CD200R/Orexin receptorHCRTR 1; HCRTR1; Hypocretin receptor type 1; Orexin receptor type 1; OX1R; CD200R; HCRTR2;
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性能参数:
中文名称:丘脑分泌素受体抗体(食欲素受体)
英文名称:Anti-CD200R/Orexin receptor
别名:HCRTR 1; HCRTR1; Hypocretin receptor type 1; Orexin receptor type 1; OX1R; CD200R; HCRTR2;
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:Several peptides associated with feeding behavior have been reported recently. Orexins (Orexin-A and Orexin-B) are a family of hypothalamic neuropeptides selectively expressed in the hypothalamus (Sakurai et al. 1998). Orexin-A and Orexin-B are derived from the same precursor (Prepro-orexin) by proteolytic cleavage. Prepro-orexin is an 130 aa peptide with a putative 33 aa secretory sequence, a hydrophobic core followed by residues with small polar side chains. The expression was detected in brain and to a small extent in testis (Sakurai et al. 1998). These neuropeptides bind and activate two closely related Orexin receptors--G protein coupled receptors (GPCRs) OX1R and OX2R.食欲素受体(OXR)Orexin receptor—是一种G蛋白偶合受体. 下丘脑是调节饮食及能量平衡的中枢.学者认为:在下丘脑可促进食欲且来源于同一前体的两种新神经肽:食欲素A和B,它们可激活两种密切相关且与G蛋白偶联的细胞表面受体(OX1R,OX2R).含Orexin的神经细胞在下丘脑腹外侧呈对称的不连贯分布. 在饮食反馈调节中具有重要作用.食欲素与其它影响进食的神经肽之间存在错综复杂的关系.它在增加摄食、饮水、调节睡眠觉醒周期、生殖、体温、血压和感觉等方面有广泛作用.丘脑分泌素受体抗体(食欲素受体)的质量标准:
■其它名称: | HCRTR 1; HCRTR1; Hypocretin receptor type 1; Orexin receptor type 1; OX1R; CD200R; HCRTR2; |
■交叉反应: | hu, mo, rat, dog, cow, hrs, chk, Rb, pig |
■产品类型: | 一抗 |
■应用领域: | /神经生物学/信号转导/通道蛋白/细胞膜受体/内分泌病/G蛋白偶联受体 |
■蛋白分子: | predicted molecular weight: 50kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from human Orexin receptor 1/2 C-terminus |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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丘脑分泌素受体抗体(食欲素受体)Anti-CD200R/Orexin receptor的相关产品目录:
1mg/1ml 丘脑分泌素受体抗体(食欲素受体) Anti-CD200R/Orexin receptor HCRTR 1; HCRTR1; Hypocretin receptor type 1; Orexin receptor type 1; OX1R; CD200R; HCRTR2;的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
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