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DNA损伤关卡蛋白1抗体 田源一抗
点击次数:101发布时间:2012/8/9 12:00:43
更新日期:2013/6/6 11:12:54
所 在 地:其它
产品型号:Anti-NFBD1/MDC1
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详细内容
DNA损伤关卡蛋白1抗体Anti-NFBD1/MDC1Nuclear factor with BRCT domains protein 1; DKFZp781A0122; Homologue to Drosophila photore
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性能参数:
中文名称:DNA损伤关卡蛋白1抗体
英文名称:Anti-NFBD1/MDC1
别名:Nuclear factor with BRCT domains protein 1; DKFZp781A0122; Homologue to Drosophila photore
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:The protein encoded by this gene contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs, and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci. [provided by RefSeq].NFBD1又称MDC1(mediator of DNA damagecheckpoint protein 1)是一个参与DNA损伤细胞应答通路的重要传递和修复因子,在DNA损伤关卡、DNA损伤修复、细胞生长增殖及肿瘤发生中均有作用。DNA损伤关卡蛋白1抗体的质量标准:
■其它名称: | Nuclear factor with BRCT domains protein 1; DKFZp781A0122; Homologue to Drosophila photore |
■交叉反应: | hu, mo, rat |
■产品类型: | 一抗 |
■应用领域: | /细胞生物/神经生物学/信号转导/细胞凋亡/转录调节因子 |
■蛋白分子: | predicted molecular weight: 230(human), 188(mo), 147(rat)kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from human NFBD1 C-terminus |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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DNA损伤关卡蛋白1抗体Anti-NFBD1/MDC1的相关产品目录:
1mg/1ml DNA损伤关卡蛋白1抗体 Anti-NFBD1/MDC1 Nuclear factor with BRCT domains protein 1; DKFZp781A0122; Homologue to Drosophila photore的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
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