磷酸化p21激活激酶2抗体Anti-phospho-PAK2（Ser141）CB422; EC 2.7.11.1; Gamma PAK; hPAK65; Kinase; p21 （CDKN1A）-activated kinase 2a; p21 activ
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性能参数：

中文名称：磷酸化p21激活激酶2抗体
英文名称：Anti-phospho-PAK2（Ser141）
别名：CB422; EC 2.7.11.1; Gamma PAK; hPAK65; Kinase; p21 （CDKN1A）-activated kinase 2a; p21 activ
包装号：G320
产地：中国大陆/进口产品
商标/品牌：Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商：田源试剂 TR、新试剂 NR
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产品详细描述

产品介绍：The p21 activated kinases （PAK） are critical effectors that link Rho GTPases to cytoskeleton reorganization ａnd nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 ａnd RAC1, ａnd have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, ａnd may play a role in regulating the apoptotic events in the dying cell.P21-activated kinase （PAK） is actually a family of serine/threonine protein kinases, members of which are activated by small molecular weight GTPases. The three most common isoforms are PAK 1, PAK 2, ａnd PAK 3 （also known as alpha PAK, gamma PAK, ａnd beta PAK, respectively）. These kinases contain numerous regulatory elements that trigger diverse signaling processes such as those initiated by activated GTPases, interaction with Src homology 3 （SH3） domains, ａnd caspase mediated proteolytic cleavage. Autophosphorylation of serine 141 （serine 144 for PAK 1 ａnd serine 139 PAK 3）, catalyzed by Cdc42, is required for activation of PAK.PAK1-3蛋白具有广泛的生物学功能,也是一个保守的丝氨酸/苏氨酸蛋白激酶,参与许多重要的细胞活动。包括细胞骨架的动力学调节,细胞移动,生存和凋亡,细胞周期,基因转录调节,细胞生长信号转导和转化等。

磷酸化p21激活激酶2抗体的质量标准：

■其它名称：	CB422; EC 2.7.11.1; Gamma PAK; hPAK65; Kinase; p21 （CDKN1A）-activated kinase 2a; p21 activ
■交叉反应：	hu, mo, rat
■产品类型：	一抗磷酸化抗体
■应用领域:	/肿瘤/细胞生物/神经生物学/信号转导/细胞凋亡/转录调节因子/激酶和磷酸酶
■蛋白分子：	predicted molecular weight: 58kDa
■浓度值：	1mg/1ml
■物理性状：	Lyophilized or Liquid
■免疫原：	KLH conjugated Synthesised phosphopeptide derived from human PAK2 around the phosphorylation site of （Ser141）
■亚型：	polyclonal
■纯化方法：	affinity purified by Protein A
■保存液：	0.01M PBS, pH 7.4 with 10 mg/ml BSA ａnd 0.1% Sodium azide
■应用技术：	//WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500（石蜡切片需做抗原修复）/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user.
■保存环境：	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

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由于化学产品的特殊性，恕不接受以下投诉：
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磷酸化p21激活激酶2抗体Anti-phospho-PAK2（Ser141）的相关产品目录：







1mg/1ml 磷酸化p21激活激酶2抗体 Anti-phospho-PAK2（Ser141） CB422; EC 2.7.11.1; Gamma PAK; hPAK65; Kinase; p21 （CDKN1A）-activated kinase 2a; p21 activ的来源为Rabbit，其相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗

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