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磷酸化磷脂酰肌醇激酶抗体 田源一抗磷酸化抗体
点击次数:116发布时间:2012/8/10 11:15:27
更新日期:2013/6/6 11:07:27
所 在 地:其它
产品型号:Anti-phospho-PI3K p85(Tyr458)/p55(Tyr199)
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详细内容
磷酸化磷脂酰肌醇激酶抗体Anti-phospho-PI3K p85(Tyr458)/p55(Tyr199)GRB1; p50 alpha; p55 alpha; p85 alpha; p85; Phosphatidylinositol 3 kinase associated p85 a
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中文名称:磷酸化磷脂酰肌醇激酶抗体
英文名称:Anti-phospho-PI3K p85(Tyr458)/p55(Tyr199)
别名:GRB1; p50 alpha; p55 alpha; p85 alpha; p85; Phosphatidylinositol 3 kinase associated p85 a
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:The enzyme phosphatidylinositol 3 kinase (PI3 kinase) is a lipid kinase that generates phosphatidylinositol 3, 4, 5-triphosphate in response to receptor activation in many signal transduction pathways. Class IA PI3Ks exist as a heterodimer of a catalytic 110 kDa (p110) and a regulatory p85 subunit (e.g. p85 alpha). p85 alpha is an adaptor molecule that regulates the activity of the catalytic p110 subunit by binding to phosphorylated receptor tyrosine kinases (RTKs) through its SH2 domain and mediating the interaction between p110 and the plasma membrane. p85 alpha is necessary for insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues.Tissue Specificity : Highest levels in brain and testis. Lower levels in adipose tissue, kidney, heart, lung and skeletal muscle.Similarity : Belongs to the PI3K p85 subunit family. Contains 2 SH2 domains.Subunit : Heterodimer of a regulatory subunit PIK3R3 and a p110 catalytic subunit (PIK3CA, PIK3CB or PIK3CD).磷酸化磷脂酰肌醇激酶抗体的质量标准:
■其它名称: | GRB1; p50 alpha; p55 alpha; p85 alpha; p85; Phosphatidylinositol 3 kinase associated p85 a |
■交叉反应: | hu, mo, rat, dog, hrs, pig, cow, Rb |
■产品类型: | 一抗磷酸化抗体 |
■应用领域: | /肿瘤/免疫学/信号转导/细胞凋亡/转录调节因子/激酶和磷酸酶 |
■蛋白分子: | predicted molecular weight: 85kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated Synthesised phosphopeptide derived from human PI3K around the phosphorylation site of p85 Tyr458 |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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磷酸化磷脂酰肌醇激酶抗体Anti-phospho-PI3K p85(Tyr458)/p55(Tyr199)的相关产品目录:
1mg/1ml 磷酸化磷脂酰肌醇激酶抗体 Anti-phospho-PI3K p85(Tyr458)/p55(Tyr199) GRB1; p50 alpha; p55 alpha; p85 alpha; p85; Phosphatidylinositol 3 kinase associated p85 a的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
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