磷酸化丝/苏氨酸蛋白激酶Plk1抗体Anti-Phospho-PLK1（Thr210）Polo-Like Kinase（phospho T210）; PLK 1; PLK; polio like kinase; Polo like kinase 1; Polo-li
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性能参数：

中文名称：磷酸化丝/苏氨酸蛋白激酶Plk1抗体
英文名称：Anti-Phospho-PLK1（Thr210）
别名：Polo-Like Kinase（phospho T210）; PLK 1; PLK; polio like kinase; Polo like kinase 1; Polo-li
包装号：G320
产地：中国大陆/进口产品
商标/品牌：Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商：田源试剂 TR、新试剂 NR
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产品详细描述

产品介绍：PLK1 （polo-like kinase 1） is a member of the serine/threonine protein kinase family, cdc5/polo subfamily. PLK1 contains two polo box domains with a predicted molecular weight of 68 kDa. PLK1 has been shown to regulate cdc2/cyclin B through phosphorylation ａnd activation of cdc25c phosphatase. PLK1 is modified by phosphorylation at Threonine 210. PLK1 may also be required for cell division. Depletion of PLK1 results in apoptosis ａnd deregulation of expression of PKL1 is correlated with development of many malignancies.Subcellular Location : Nucleus. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, centrosome. Midbody.Tissue Specificity : Placenta ａnd colon.Similarity : Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily. Contains 2 POLO box domains. Contains 1 protein kinase domain.Subunit : Interacts with CEP170 ａnd EVI5. Interacts ａnd phosphorylates ERCC6L. Interacts with FAM29A. Interacts with SLX4/BTBD12 ａnd TTDN1. Interacts with BUB1B. Interacts （via POLO-box domain） with the phosphorylated form of BUB1, MLF1IP ａnd CDC25C. Interacts with isoform 3 of SGOL1. Interacts with BORA, KIF2A ａnd AURKA. Interacts with TOPORS ａnd CYLD. Interacts with ECT2; the interaction is stimulated upon phosphorylation of ECT2 on ＇Thr-444＇. Interacts with PRC1.

磷酸化丝/苏氨酸蛋白激酶Plk1抗体的质量标准：

■其它名称：	Polo-Like Kinase（phospho T210）; PLK 1; PLK; polio like kinase; Polo like kinase 1; Polo-li
■交叉反应：	hu, mo, rat, pig, dog, chk, cow,Rb
■产品类型：	一抗磷酸化抗体
■应用领域:	/肿瘤/免疫学/信号转导/转录调节因子/激酶和磷酸酶
■蛋白分子：	predicted molecular weight: 68kDa
■浓度值：	1mg/1ml
■物理性状：	Lyophilized or Liquid
■免疫原：	KLH conjugated synthesised phosphopeptide derived from human PLK1 around the phosphorylation site of Thr210
■亚型：	polyclonal
■纯化方法：	affinity purified by Protein A
■保存液：	0.01M PBS, pH 7.4 with 10 mg/ml BSA ａnd 0.1% Sodium azide
■应用技术：	//WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500（石蜡切片需做抗原修复）/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user.
■保存环境：	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

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磷酸化丝/苏氨酸蛋白激酶Plk1抗体Anti-Phospho-PLK1（Thr210）的相关产品目录：







1mg/1ml 磷酸化丝/苏氨酸蛋白激酶Plk1抗体 Anti-Phospho-PLK1（Thr210） Polo-Like Kinase（phospho T210）; PLK 1; PLK; polio like kinase; Polo like kinase 1; Polo-li的来源为Rabbit，其相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗

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