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磷酸化p21激活激酶1抗体 田源一抗磷酸化抗体
点击次数:94发布时间:2012/8/10 11:19:20
更新日期:2013/6/6 11:06:53
所 在 地:其它
产品型号:Anti-phospho-PAK1(Thr212)
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详细内容
磷酸化p21激活激酶1抗体Anti-phospho-PAK1(Thr212)PAK1(Phospho-Thr212); PAK1(phospho T212); Alpha PAK; Beta PAK; Gamma PAK; Oligophrenin 3;
360TIYO.COM-上海田源公司
性能参数:
中文名称:磷酸化p21激活激酶1抗体
英文名称:Anti-phospho-PAK1(Thr212)
别名:PAK1(Phospho-Thr212); PAK1(phospho T212); Alpha PAK; Beta PAK; Gamma PAK; Oligophrenin 3;
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell.Subcellular Location : Cytoplasm. Cell junction, focal adhesion.Similarity : Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.Contains 1 CRIB domain.Contains 1 protein kinase domain.Subunit : Homodimer in its autoinhibited state. PAK1-3蛋白具有广泛的生物学功能,也是一个保守的丝氨酸/苏氨酸蛋白激酶,参与许多重要的细胞活动。包括细胞骨架的动力学调节,细胞移动,生存和凋亡,细胞周期,基因转录调节,细胞生长信号转导和转化等。磷酸化p21激活激酶1抗体的质量标准:
■其它名称: | PAK1(Phospho-Thr212); PAK1(phospho T212); Alpha PAK; Beta PAK; Gamma PAK; Oligophrenin 3; |
■交叉反应: | hu, mo, rat, dog, Rb |
■产品类型: | 一抗磷酸化抗体 |
■应用领域: | /肿瘤/免疫学/信号转导/转录调节因子/激酶和磷酸酶 |
■蛋白分子: | predicted molecular weight: 60kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated Synthesised phosphopeptide derived from human PAK1 around the phosphorylation site of Thr212 |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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磷酸化p21激活激酶1抗体Anti-phospho-PAK1(Thr212)的相关产品目录:
1mg/1ml 磷酸化p21激活激酶1抗体 Anti-phospho-PAK1(Thr212) PAK1(Phospho-Thr212); PAK1(phospho T212); Alpha PAK; Beta PAK; Gamma PAK; Oligophrenin 3; 的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
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