产品展示
磷酸化血小板源性生长因子受体-α抗体 田源一抗磷酸化抗体
点击次数:141发布时间:2012/8/10 11:19:24
更新日期:2013/6/6 11:06:53
所 在 地:其它
产品型号:Anti-Phospho-PDGFRA(Tyr754)
优质供应
详细内容
磷酸化血小板源性生长因子受体-α抗体Anti-Phospho-PDGFRA(Tyr754)PDGF Receptor alpha; Platelet–dirived growth factor receptor-alpha; Alpha platelet derived
360TIYO.COM-上海田源公司
性能参数:
中文名称:磷酸化血小板源性生长因子受体-α抗体
英文名称:Anti-Phospho-PDGFRA(Tyr754)
别名:PDGF Receptor alpha; Platelet–dirived growth factor receptor-alpha; Alpha platelet derived
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
----------------------------------------------------------
产品详细描述
产品介绍:The PDGF Receptor Type A (Alpha platelet-derived growth factor receptor precursor, CD140a antigen), a 170kD protein, binds all three isoforms of PDGF with high affinity whereas the PDGF Receptor Type B, a 190kD protein, appears to bind only the PDGF BB homodimer with high affinity. Both receptors are transmembranous, ligand activated protein tyrosine kinases, which phosphorylate a number of important signal transduction proteins, which are bound with differential affinities via SH2 domains. The response of any given cell to PDGF will depend on the types of receptors displayed on the surface and isoforms of PDGF present in the extracellular environment.细胞膜受体(Membrane Receptors)PDGFR-α是膜受体,具有酪氨酸酶的活性,与其配体PDGF结合后激活与细胞增殖有关的酶及基因。 PDGFR亦表达于上皮、内皮细胞,前列腺、皮肤、肾小球等上皮细胞均有PDGFR表达. 亦有学者报道血小板源性生长因子受体α抗体在细胞胞浆胞膜、胞核都有不同的表达还有人认为:PDGF及其受体一般表达于浸润病变组织的炎症细胞附近,组织缺血损伤、肾小球高压、免疫因素作用、炎症细胞浸润、实质细胞活化等导致PDGFR表达增强。磷酸化血小板源性生长因子受体-α抗体的质量标准:
■其它名称: | PDGF Receptor alpha; Platelet–dirived growth factor receptor-alpha; Alpha platelet derived |
■交叉反应: | hu, mo, rat |
■产品类型: | 一抗磷酸化抗体 |
■应用领域: | /肿瘤/免疫学/细胞凋亡/转录调节因子/激酶和磷酸酶/细胞膜受体 |
■蛋白分子: | predicted molecular weight: 170kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated Synthesised phosphopeptide derived from human PDGF Receptor alpha around the phosphorylation site of Tyr754 |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
----------------------------------------------------------
质量投诉流程
1、向我们的客户服务部反应投诉原因及订单信息。
2、向我们发送投诉相关的证明材料。
3、田源时间进行质量投诉调查及处理调查结果。
4、田源将联系客户并提供质量投诉处理结果。
友情提醒:
部分进口产品投诉须按照进口产品要求的检测方法提供证据。
由于化学产品的特殊性,恕不接受以下投诉:
1、超过质量投诉期的进口产品投诉
2、非质量报告提及的指标投诉
磷酸化血小板源性生长因子受体-α抗体Anti-Phospho-PDGFRA(Tyr754)的相关产品目录:
1mg/1ml 磷酸化血小板源性生长因子受体-α抗体 Anti-Phospho-PDGFRA(Tyr754) PDGF Receptor alpha; Platelet–dirived growth factor receptor-alpha; Alpha platelet derived的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
查询其它抗体目录请点击本公司化工仪器网链接:http://www.chem17.com/st233816/erlist_675408.html
上海田源专业销售磷酸化血小板源性生长因子受体-α抗体 Anti-Phospho-PDGFRA(Tyr754),了解更多请点击查询!