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增殖细胞核抗原抗体 田源一抗
点击次数:94发布时间:2012/8/10 11:23:39
更新日期:2013/6/26 17:16:08
所 在 地:其它
产品型号:Anti-PCNA-Proliferation Marker
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详细内容
增殖细胞核抗原抗体Anti-PCNA-Proliferation MarkerCyclin; DNA polymerase delta auxiliary protein; HGCN8729; MGC8367; Mutagen-sensitive 209
360TIYO.COM-上海田源公司
性能参数:
中文名称:增殖细胞核抗原抗体
英文名称:Anti-PCNA-Proliferation Marker
别名:Cyclin; DNA polymerase delta auxiliary protein; HGCN8729; MGC8367; Mutagen-sensitive 209
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:Proliferation Marker Proliferating cell nuclear antigen (PCNA) is a 28kDa nuclear protein associated with the cell cycle, a nuclear protein vital for cellular DNA synthesis. Proliferating cell nuclear antigen was originally identified by immunofluorescence as a nuclear protein whose appearance correlated with the proliferate state of the cell. PCNA is required for replication of DNA in vitro and has been identified as the auxiliary protein (cofactor) for DNA polymerase delta. The anti-PCNA antibodies react with the nuclei of proliferating cells. PCNA is essential for cellular DNA synthesis and is also required for the in vitro replication of simian virus 40 (SV40) DNA where it acts to coordinate leading and lagging strand synthesis at the replication fork. The PCNA protein may fulfil several separate roles in the cell nucleus associated with changes in its antigenic structure.PCNA是一种仅在增殖细胞中合成或表达的核内多肽,其表达和合成与细胞周期有关。主要表达于增殖细胞的S期、G1期和G2初期。 PCNA主要作为判断各种恶性肿瘤(包括胃肠道癌肿、乳腺癌、肝癌、膀胱癌等)细胞增殖和其恶性程度的一种指标.增殖细胞核抗原抗体的质量标准:
■其它名称: | Cyclin; DNA polymerase delta auxiliary protein; HGCN8729; MGC8367; Mutagen-sensitive 209 |
■交叉反应: | hu, mo, rat, Rb, cow, dog, chk |
■产品类型: | 一抗 |
■应用领域: | /肿瘤/细胞生物/染色质和核信号/细胞周期蛋白/转录调节因子 |
■蛋白分子: | predicted molecular weight: 29skDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from human PCNA C-terminus |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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增殖细胞核抗原抗体Anti-PCNA-Proliferation Marker的相关产品目录:
1mg/1ml 增殖细胞核抗原抗体 Anti-PCNA-Proliferation Marker Cyclin; DNA polymerase delta auxiliary protein; HGCN8729; MGC8367; Mutagen-sensitive 209的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
查询其它抗体目录请点击本公司化工仪器网链接:http://www.chem17.com/st233816/erlist_675408.html
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