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肝癌高表达基因抗体 田源一抗
点击次数:185发布时间:2012/8/10 11:23:41
更新日期:2013/6/26 17:16:08
所 在 地:其它
产品型号:Anti-PEG10
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详细内容
肝癌高表达基因抗体Anti-PEG10Paternally expressed gene 10; MyEF 3; AA407948; Edr; Embryonal carcinoma differentiation r
360TIYO.COM-上海田源公司
性能参数:
中文名称:肝癌高表达基因抗体
英文名称:Anti-PEG10
别名:Paternally expressed gene 10; MyEF 3; AA407948; Edr; Embryonal carcinoma differentiation r
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:PEG10 (Paternally expressed gene 10) inhibits TGF beta signaling by interacting with the TGF beta receptor ALK1. It is able to prevent apoptosis in hepatocellular carcinoma (HCC) cells through interaction with SIAH1, a mediator of apoptosis. PEG10 is a mammalian gene that has been shown to be essential for embryonic development and is highly conserved in therian mammals. PEG10 has evolved from a retroelement into a gene that is required during prenatal development and has maintained its ability to carry out –1 frameshifting to express two proteins from the same mRNA (ORF1 and ORF2). This is the first demonstration of –1 frameshifting for gene expression in animal tissues and is the highest frameshift efficiency reported.PEG10是一个癌基因,在肿瘤癌变过程中起重要作用。PEG10在原发性肝癌中表达明显上调,体外细胞试验证明PEG10影响细胞周期,可促进细胞生长,在肝细胞癌变过程中起重要作用。肝癌高表达基因抗体的质量标准:
■其它名称: | Paternally expressed gene 10; MyEF 3; AA407948; Edr; Embryonal carcinoma differentiation r |
■交叉反应: | hu, mo, rat, pig, cow, dog |
■产品类型: | 一抗 |
■应用领域: | /肿瘤/细胞生物 |
■蛋白分子: | predicted molecular weight: 36/78kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from human PEG10 C-terminus |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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肝癌高表达基因抗体Anti-PEG10的相关产品目录:
1mg/1ml 肝癌高表达基因抗体 Anti-PEG10 Paternally expressed gene 10; MyEF 3; AA407948; Edr; Embryonal carcinoma differentiation r的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
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