磷酸二酯酶5A抗体Anti-PDE5ACGB PDE; CGBPDE; cGMP binding cGMP specific 3＇ 5＇ cyclic nucleotide phosphodiesterase; cGM
360TIYO.COM-上海田源公司

性能参数：

中文名称：磷酸二酯酶5A抗体
英文名称：Anti-PDE5A
别名：CGB PDE; CGBPDE; cGMP binding cGMP specific 3＇ 5＇ cyclic nucleotide phosphodiesterase; cGM
包装号：G320
产地：中国大陆/进口产品
商标/品牌：Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商：田源试剂 TR、新试剂 NR
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产品详细描述

产品介绍：The cGMP specific phosphodiesterase type 5A （PDE5A） family is comprised of 2 genes （PDE5A ａnd PDE5B） each with multiple splice variants generated by RNA splicing ａnd use of alternate initiation sites. The PDE5 is highly expressed in aorta ａnd lungs, intestine, kidney adrenal gland cerebellum ａnd cerebrum. In cerebellum the PDE5 is highly expressed during neonatal development in Purkinge cells layer. The PDE5 is also abundant in vascular smooth muscle regulating cGMP levels ａnd vascular smooth muscle tonicity. In corpus cavernosum inhibition of PDE5 by sildenafil corrects erectile dysfunctions. The nitric oxide donor sodium notropurside （SNP） stimulate PDE5 activity by cGMP dependent kinase phosphorylation. PDE5A1 has 875 amino acids （99.5 kDa）. The amino terminal 142 amino acid of the PDE5 gene showed no sequence homology with other PDEs ａnd also contained serine 92 that is phosphorylated by cGMP kinases.Tissue Specificity : Expressed in aortic smooth muscle cells, heart, placenta, skeletal muscle ａnd pancreas and, to a much lesser extent, in brain, liver ａnd lung.Similarity : Belongs to the cyclic nucleotide phosphodiesterase family.Contains 2 GAF domains.

磷酸二酯酶5A抗体的质量标准：

■其它名称：	CGB PDE; CGBPDE; cGMP binding cGMP specific 3＇ 5＇ cyclic nucleotide phosphodiesterase; cGM
■交叉反应：	hu, mo, rat, hrs, cow, shp, Gpig, pig, Rb, dog, chk
■产品类型：	一抗
■应用领域:	/肿瘤/免疫学/染色质和核信号/信号转导/转录调节因子
■蛋白分子：	predicted molecular weight: 96kDa
■浓度值：	1mg/1ml
■物理性状：	Lyophilized or Liquid
■免疫原：	KLH conjugated synthetic peptide derived from human PDE5A
■亚型：	polyclonal
■纯化方法：	affinity purified by Protein A
■保存液：	0.01M PBS, pH 7.4 with 10 mg/ml BSA ａnd 0.1% Sodium azide
■应用技术：	//WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500（石蜡切片需做抗原修复）/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user.
■保存环境：	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

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质量投诉流程
1、向我们的客户服务部反应投诉原因及订单信息。
2、向我们发送投诉相关的证明材料。
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友情提醒：
部分进口产品投诉须按照进口产品要求的检测方法提供证据。
由于化学产品的特殊性，恕不接受以下投诉：
1、超过质量投诉期的进口产品投诉
2、非质量报告提及的指标投诉

磷酸二酯酶5A抗体Anti-PDE5A的相关产品目录：







1mg/1ml 磷酸二酯酶5A抗体 Anti-PDE5A CGB PDE; CGBPDE; cGMP binding cGMP specific 3＇ 5＇ cyclic nucleotide phosphodiesterase; cGM的来源为Rabbit，其相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗

查询其它抗体目录请点击本公司化工仪器网链接：http://www.chem17.com/st233816/erlist_675408.html

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