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纤溶酶原激活物抑制因子2抗体(血浆酶原激活酶抑制因子-2) 田源一抗
点击次数:184发布时间:2012/8/10 11:25:59
更新日期:2013/6/26 17:15:24
所 在 地:其它
产品型号:Anti-PAI-2/SerpinB2
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详细内容
纤溶酶原激活物抑制因子2抗体(血浆酶原激活酶抑制因子-2)Anti-PAI-2/SerpinB2SerpinB2; plasminogen activator inhibitor 2; HsT1201; Monocyte Arg serpin; PAI 2; PAI2; Pl
360TIYO.COM-上海田源公司
性能参数:
中文名称:纤溶酶原激活物抑制因子2抗体(血浆酶原激活酶抑制因子-2)
英文名称:Anti-PAI-2/SerpinB2
别名:SerpinB2; plasminogen activator inhibitor 2; HsT1201; Monocyte Arg serpin; PAI 2; PAI2; Pl
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:SerpinB2 is a serine proteinase inhibitor of the ovalbumin like B clade of serpins. It was first discovered in the placenta, and given the name PAI-2 because of the ability to inhibit urokinase plasminogen activator (u-PA) at low micromolar efficiency. SerpinB2 also inhibits tissue plasminogen activator (t-PA), but with micromolar efficiency, and PAI-1 is much more efficient that SerpinB2 on both forms of plasminogen activator. The structure of PAI-2 is not terribly similar to PAI-1, however, which is an E clade serpin. SerpinB2 is made by many cell types, and is found intracellularly as an unglycosylated kDa protein, and secreted as a 60 kDa protein. SerpinB2 is found in saliva, secreted by gingival fibroblasts, and in the skin. SerpinB2 levels are elevated in serum during pregnancy, and in leukemia, breast cancer and ovarian cancer, although it was lowered in some cancers.A shorter SerpinB2 isoform of 382 amino acids, has been reported, with a predicted mass of 43.1 kDa and a pI of 5.69. The shorter form has a deletion just after the start of the mature protein, but it is unclear what the relative production and distribution is for the shorter sequence.Subcellular Location : Cytoplasm. Secreted, extracellular space.Similarity : Belongs to the serpin family. Ov-serpin subfamily.Subunit : Interacts with PSMB1.纤溶酶原激活物抑制因子2抗体(血浆酶原激活酶抑制因子-2)的质量标准:
■其它名称: | SerpinB2; plasminogen activator inhibitor 2; HsT1201; Monocyte Arg serpin; PAI 2; PAI2; Pl |
■交叉反应: | hu, mo, rat, Rb, pig, dog, cow |
■产品类型: | 一抗 |
■应用领域: | /细胞生物/免疫学 |
■蛋白分子: | predicted molecular weight: 47kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from human PAI-2 C-terminus |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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纤溶酶原激活物抑制因子2抗体(血浆酶原激活酶抑制因子-2)Anti-PAI-2/SerpinB2的相关产品目录:
1mg/1ml 纤溶酶原激活物抑制因子2抗体(血浆酶原激活酶抑制因子-2) Anti-PAI-2/SerpinB2 SerpinB2; plasminogen activator inhibitor 2; HsT1201; Monocyte Arg serpin; PAI 2; PAI2; Pl的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
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