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血小板源性生长因子-B抗体 田源一抗
点击次数:162发布时间:2012/8/13 14:06:53
更新日期:2013/6/26 17:12:45
所 在 地:其它
产品型号:Anti-PDGF-B
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详细内容
血小板源性生长因子-B抗体Anti-PDGF-BPDGF-B; Platelet-derived growth factor B-chain;PDGF AB + BB;Becaplermin;c sis;FLJ1
360TIYO.COM-上海田源公司
性能参数:
中文名称:血小板源性生长因子-B抗体
英文名称:Anti-PDGF-B
别名:PDGF-B; Platelet-derived growth factor B-chain;PDGF AB + BB;Becaplermin;c sis;FLJ1
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. Binding of this growth factor to its affinity receptor elicits a variety of cellular responses. It is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heal the wound. [SUBUNIT] Antiparallel disulfide-linked dimer of nonidentical (A and B) chains. Homodimers of A and B chains are implicated in transformation processes. A-A and B-B, as well as A-B, dimers can bind to the PDGF receptor. Belongs to the PDGF/VEGF growth factor family.Subcellular Location : Secreted.Tissue Specificity : Expressed at high levels in the heart, brain (sustantia nigra), placenta and fetal kidney. Expressed at moderate levels in the brain (hippocampus), skeletal muscle, kidney and lung.Similarity : Belongs to the PDGF/VEGF growth factor family.Subunit : Homodimer; antiparallel disulfide-linked dimer. Heterodimer with PDGFA; antiparallel disulfide-linked dimer. The PDGFB homodimer interacts with PDGFRA and PDGFRB homodimers, and with heterodimers formed by PDGFRA and PDGFRB. The heterodimer composed of PDGFA and PDGFB interacts with PDGFRB homodimers, and with heterodimers formed by PDGFRA and PDGFRB. Interacts with XLKD1.生长因子和激素( Growth Factor and Hormones) PDGF(platelet-dirived growth factor)是一种碱性蛋白,分为两个亚基(A、B链)通过二硫键结合而成的两条多肽链的异二聚体,分子量为28-35kDa。为促细胞分裂剂,可使小鼠成纤维细胞及其他多种细胞增殖。研究发现了PDGF家族两种新的基因PDGF-C、PDGF-D。血小板源性生长因子-B抗体的质量标准:
■其它名称: | PDGF-B; Platelet-derived growth factor B-chain;PDGF AB + BB;Becaplermin;c sis;FLJ1 |
■交叉反应: | hu, rat, mo, Rb, dog, hrs, cow, shp |
■产品类型: | 一抗 |
■应用领域: | /心血管/信号转导/生长因子和激素 |
■蛋白分子: | predicted molecular weight: 27kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from human PDGF-B C-terminus |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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由于化学产品的特殊性,恕不接受以下投诉:
1、超过质量投诉期的进口产品投诉
2、非质量报告提及的指标投诉
血小板源性生长因子-B抗体Anti-PDGF-B的相关产品目录:
1mg/1ml 血小板源性生长因子-B抗体 Anti-PDGF-B PDGF-B; Platelet-derived growth factor B-chain;PDGF AB + BB;Becaplermin;c sis;FLJ1的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
查询其它抗体目录请点击本公司化工仪器网链接:http://www.chem17.com/st233816/erlist_675408.html
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