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mTOR相关调控蛋白抗体 田源一抗

点击次数:158发布时间:2012/8/13 14:08:36

mTOR相关调控蛋白抗体 田源一抗

更新日期:2013/6/26 17:11:38

所 在 地:其它

产品型号:Anti-Raptor

简单介绍:mTOR相关调控蛋白抗体价格查询,mTOR相关调控蛋白抗体现货供应!别名:Anti-Raptor p150 target of rapamycin (TOR) scaffold protein containing WD repeats; P150 target of rapa。专业抗体产品生产和代理销售商,田源商标!

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详细内容

mTOR相关调控蛋白抗体Anti-Raptorp150 target of rapamycin (TOR) scaffold protein containing WD repeats; P150 target of rapa
360TIYO.COM-上海田源公司


性能参数:


中文名称:mTOR相关调控蛋白抗体
英文名称:Anti-Raptor
别名:p150 target of rapamycin (TOR) scaffold protein containing WD repeats; P150 target of rapa
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述

产品介绍:mTOR controls cell growth, in part by regulating p70 S6 kinase alpha (p70alpha) and eukaryotic initiation factor 4E binding protein 1 (4EBP1). Raptor is a 150 kDa mTOR binding protein that also binds 4EBP1 and p70alpha. The binding of Raptor to mTOR is necessary for the mTOR-catalyzed phosphorylation of 4EBP1 in vitro, and it strongly enhances the mTOR kinase activity toward p70alpha. Rapamycin or amino acid withdrawal increases, whereas insulin strongly inhibits, the recovery of 4EBP1 and raptor on 7-methyl-GTP Sepharose. Partial inhibition of raptor expression by RNA interference (RNAi) reduces mTOR-catalyzed 4EBP1 phosphorylation in vitro. RNAi of C. elegans raptor yields an array of phenotypes that closely resemble those produced by inactivation of Ce-TOR. Thus, raptor is an essential scaffold for the mTOR-catalyzed phosphorylation of 4EBP1 and mediates TOR action in vivo.Subcellular Location : Cytoplasm. Lysosome.Tissue Specificity : Highly expressed in skeletal muscle, and in a lesser extent in brain, lung, small intestine, kidney and placenta.Similarity : Belongs to the WD repeat RAPTOR family.Contains 7 WD repeats.Subunit : Interacts with MTOR.乳类雷帕霉素靶蛋白(mTOR)信号通路是涉及细胞增长、肿瘤、炎症、和纤维化的重要信号通路,其相关分子Raptor也是目前的研究热点。

mTOR相关调控蛋白抗体的质量标准:
■其它名称:p150 target of rapamycin (TOR) scaffold protein containing WD repeats; P150 target of rapa
■交叉反应:hu, mo, rat, cow, hrs, chk, dog, Rb
■产品类型:一抗
■应用领域:/肿瘤/免疫学/信号转导/细胞凋亡/转录调节因子
■蛋白分子:predicted molecular weight: 147kDa
■浓度值:1mg/1ml
■物理性状:Lyophilized or Liquid
■免疫原:KLH conjugated synthetic peptide derived from human Raptor
■亚型:polyclonal
■纯化方法:affinity purified by Protein A
■保存液:0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
■应用技术://WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user.
■保存环境:Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

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1、向我们的客户服务部反应投诉原因及订单信息。
2、向我们发送投诉相关的证明材料。
3、田源时间进行质量投诉调查及处理调查结果。
4、田源将联系客户并提供质量投诉处理结果。

友情提醒:
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由于化学产品的特殊性,恕不接受以下投诉:
1、超过质量投诉期的进口产品投诉
2、非质量报告提及的指标投诉


mTOR相关调控蛋白抗体Anti-Raptor的相关产品目录:







1mg/1ml mTOR相关调控蛋白抗体 Anti-Raptor p150 target of rapamycin (TOR) scaffold protein containing WD repeats; P150 target of rapa的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗

查询其它抗体目录请点击本公司化工仪器网链接:http://www.chem17.com/st233816/erlist_675408.html

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