P选择素抗体Anti-P-selectin/CD62pSELP; selectin, platelet; P-selectin precursor; Granule membrane protein 140; GMP-140; PAD
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性能参数：

中文名称：P选择素抗体
英文名称：Anti-P-selectin/CD62p
别名：SELP; selectin, platelet; P-selectin precursor; Granule membrane protein 140; GMP-140; PAD
包装号：G320
产地：中国大陆/进口产品
商标/品牌：Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商：田源试剂 TR、新试剂 NR
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产品详细描述

产品介绍：SELPLG is the high affinity counter-receptor for P-selectin on myeloid cells ａnd stimulated T lymphocytes. As such, it plays a critical role in the tethering of these cells to activated platelets or endothelia expressing P-selectin. The organization of the SELPG gene closely resembles that of CD43 ａnd the human platelet glycoprotein GpIb-alpha both of which have an intron in the 5-prime-noncoding region, a long second exon containing the complete coding region, ａnd TATA-less promoters.Subcellular Location : Membrane; Single-pass type I membrane protein.Tissue Specificity : Stored in the alpha-granules of platelets ａnd Weibel-Palade bodies of endothelial cells. Upon cell activation by agonists, P-selectin is transported rapidly to the cell surface.Similarity : Belongs to the selectin/LECAM family.Contains 1 C-type lectin domain. Contains 1 EGF-like domain. Contains 9 Sushi （CCP/SCR） domains.Subunit : Interacts with SNX17. Interacts with PSGL1/SEPL ａnd PODXL2 ａnd mediates neutrophil adhesion ａnd leukocyte rolling. This interaction requires the sialyl-Lewis X epitope of PSGL1 ａnd PODXL2, ａnd specific tyrosine sulfation on PSGL1.P-选择素（P—selectin）是细胞黏附分子选择素家族的主要成员，又称CD62p，可以介导各种白细胞和肿瘤细胞的粘附。CD62p又称GMP—140或PADGEM蛋白（血小板活化依赖α颗粒膜蛋白）,它在血小板与单核细胞及中性粒细胞相互作用中起关键作用。

P选择素抗体的质量标准：

■其它名称：	SELP; selectin, platelet; P-selectin precursor; Granule membrane protein 140; GMP-140; PAD
■交叉反应：	mo, rat, hu, pig, cow, dog, hrs
■产品类型：	一抗
■应用领域:	/细胞生物/免疫学/细胞粘附分子/上皮细胞
■蛋白分子：	predicted molecular weight: 84/66/54/91kDa
■浓度值：	1mg/1ml
■物理性状：	Lyophilized or Liquid
■免疫原：	KLH conjugated synthetic peptide derived from human P-selectin C-terminus
■亚型：	polyclonal
■纯化方法：	affinity purified by Protein A
■保存液：	0.01M PBS, pH 7.4 with 10 mg/ml BSA ａnd 0.1% Sodium azide
■应用技术：	//WB=1:100-500//ELISA=1:500-1000//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500（石蜡切片需做抗原修复）/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user.
■保存环境：	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

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质量投诉流程
1、向我们的客户服务部反应投诉原因及订单信息。
2、向我们发送投诉相关的证明材料。
3、田源时间进行质量投诉调查及处理调查结果。
4、田源将联系客户并提供质量投诉处理结果。

友情提醒：
部分进口产品投诉须按照进口产品要求的检测方法提供证据。
由于化学产品的特殊性，恕不接受以下投诉：
1、超过质量投诉期的进口产品投诉
2、非质量报告提及的指标投诉

P选择素抗体Anti-P-selectin/CD62p的相关产品目录：







1mg/1ml P选择素抗体 Anti-P-selectin/CD62p SELP; selectin, platelet; P-selectin precursor; Granule membrane protein 140; GMP-140; PAD的来源为Rabbit，其相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗

查询其它抗体目录请点击本公司化工仪器网链接：http://www.chem17.com/st233816/erlist_675408.html

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