磷酸化孕激素受体抗体Anti-Phospho-Progesterone Receptor（Ser190）PGR（phospho S190）; NR3C3; Nuclear receptor subfamily 3 group C member 3; PGR; PR; PRA; PRB
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性能参数：

中文名称：磷酸化孕激素受体抗体
英文名称：Anti-Phospho-Progesterone Receptor（Ser190）
别名：PGR（phospho S190）; NR3C3; Nuclear receptor subfamily 3 group C member 3; PGR; PR; PRA; PRB
包装号：G320
产地：中国大陆/进口产品
商标/品牌：Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商：田源试剂 TR、新试剂 NR
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产品详细描述

产品介绍：Estrogen ａnd progesterone receptor are members of a family of transcription factors that are regulated by the binding of their cognate ligands. The interaction of hormone-bound estrogen receptors with estrogen responsive elements（EREs） alters transcription of ERE-containing genes. The carboxy terminal region of the estrgen receptor contains the ligand binding domain, the amino terminus serves as the transactivation domain, ａnd the DNA binding domain is centrally located. Two forms of estrogen receptor have been identified, ER alpha ａnd ER beta. ER alpha ａnd ER beta have been shown to be differentially activated by various ligands. The biological response to progesterone is mediated by two distinct forms of the human progesterone receptor （hPR-Aand hPR-B）, which arise from alternative splicing. In most cells, hPR-B functions as a transcriptional activator of progesterone-responsive gene, whereas hPR-A function as a transcriptional inhibitor of all steroid hormone receptors.Subcellular Location : Nucleus. Cytoplasm.Tissue Specificity : Isoform A: Nucleus. Cytoplasm. Note=Mainly nuclear.Similarity : Belongs to the nuclear hormone receptor family. NR3 subfamily. Contains 1 nuclear receptor DNA-binding domain.类固醇受体（Steroid Receptors）孕激素受体是一类位于孕酮靶组织细胞内或细胞表面的特异蛋白质，特异地与孕酮结合，所形成的细胞溶质孕酮-受体复合物随后与细胞核内的DNA结合，以启动蛋白质生物合成。孕酮受体有A和B两种，受雌激素诱导，半寿期很短。

磷酸化孕激素受体抗体的质量标准：

■其它名称：	PGR（phospho S190）; NR3C3; Nuclear receptor subfamily 3 group C member 3; PGR; PR; PRA; PRB
■交叉反应：	rat, mo, cow
■产品类型：	一抗磷酸化抗体
■应用领域:	/肿瘤/染色质和核信号/信号转导/激酶和磷酸酶
■蛋白分子：	predicted molecular weight: 102kDa
■浓度值：	1mg/1ml
■物理性状：	Lyophilized or Liquid
■免疫原：	KLH conjugated Synthesised phosphopeptide derived from rat Progesterone Receptor around the phosphorylation site of Ser190
■亚型：	polyclonal
■纯化方法：	affinity purified by Protein A
■保存液：	0.01M PBS, pH 7.4 with 10 mg/ml BSA ａnd 0.1% Sodium azide
■应用技术：	//WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500（石蜡切片需做抗原修复）/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user.
■保存环境：	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

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由于化学产品的特殊性，恕不接受以下投诉：
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磷酸化孕激素受体抗体Anti-Phospho-Progesterone Receptor（Ser190）的相关产品目录：







1mg/1ml 磷酸化孕激素受体抗体 Anti-Phospho-Progesterone Receptor（Ser190） PGR（phospho S190）; NR3C3; Nuclear receptor subfamily 3 group C member 3; PGR; PR; PRA; PRB的来源为Rabbit，其相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗

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