24脱氢胆固醇还原酶抗体Anti-Seladin 1/DHCR24Seladin1; Seladin-1; DHCR24; 24 dehydrocholesterol reductase; 3-beta-hydroxysterol delta-2
360TIYO.COM-上海田源公司

性能参数：

中文名称：24脱氢胆固醇还原酶抗体
英文名称：Anti-Seladin 1/DHCR24
别名：Seladin1; Seladin-1; DHCR24; 24 dehydrocholesterol reductase; 3-beta-hydroxysterol delta-2
包装号：G320
产地：中国大陆/进口产品
商标/品牌：Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商：田源试剂 TR、新试剂 NR
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产品详细描述

产品介绍：Seladin 1 is highly expressed in brain, adrenal tissues ａnd adrenal tumours, where this enzyme catalyzes the reduction of the delta-24 double bond of sterol intermediates such as desmosterol, during cholesterol biosynthesis. In addition, Seladin 1 has an anti-apoptotic function by reducing caspase 3 activity during oxidative stress-induced apoptosis ａnd protecting cells against amyloid-beta peptide-induced apoptosis. Several studies have identified a reduction in expression levels of this enzyme in brain regions affected by Alzheimer＇s disease （hippocampus ａnd the subventricular zone）. Subcellular Location : Endoplasmic reticulum membrane; Single-pass membrane protein. Golgi apparatus membrane; Single-pass membrane protein.Tissue Specificity : Highly expressed in brain ａnd adrenal gland with moderate expression in liver, lung, spleen, prostate ａnd spinal cord. Low expression in heart, uterus ａnd prostate. Undetectable in blood cells. In the brain, strongly expressed in cortical regions, substantia nigra, caudate nucleus, hippocampus, medulla oblongata ａnd pons. In brains affected by Alzheimer disease, expression in the inferior temporal lobe is substantially lower than in the frontal cortex.Similarity : Belongs to the FAD-binding oxidoreductase/transferase type 4 family.Contains 1 FAD-binding PCMH-type domain.Subunit : Endoplasmic reticulum membrane; Single-pass membrane protein. Golgi apparatus membrane; Single-pass membrane protein.

24脱氢胆固醇还原酶抗体的质量标准：

■其它名称：	Seladin1; Seladin-1; DHCR24; 24 dehydrocholesterol reductase; 3-beta-hydroxysterol delta-2
■交叉反应：	hu, mo, rat, hrs, dog, pig, cow, Rb
■产品类型：	一抗
■应用领域:	/肿瘤/免疫学/神经生物学/信号转导/细胞凋亡/转录调节因子
■蛋白分子：	predicted molecular weight: 55/110kDa
■浓度值：	1mg/1ml
■物理性状：	Lyophilized or Liquid
■免疫原：	KLH conjugated synthetic peptide derived from human Seladin 1
■亚型：	polyclonal
■纯化方法：	affinity purified by Protein A
■保存液：	0.01M PBS, pH 7.4 with 10 mg/ml BSA ａnd 0.1% Sodium azide
■应用技术：	//WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500（石蜡切片需做抗原修复）/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user.
■保存环境：	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

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质量投诉流程
1、向我们的客户服务部反应投诉原因及订单信息。
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友情提醒：
部分进口产品投诉须按照进口产品要求的检测方法提供证据。
由于化学产品的特殊性，恕不接受以下投诉：
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2、非质量报告提及的指标投诉

24脱氢胆固醇还原酶抗体Anti-Seladin 1/DHCR24的相关产品目录：







1mg/1ml 24脱氢胆固醇还原酶抗体 Anti-Seladin 1/DHCR24 Seladin1; Seladin-1; DHCR24; 24 dehydrocholesterol reductase; 3-beta-hydroxysterol delta-2的来源为Rabbit，其相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗

查询其它抗体目录请点击本公司化工仪器网链接：http://www.chem17.com/st233816/erlist_675408.html

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