细胞周期检控Rad17蛋白抗体（复制因子C）Anti-Rad17/RFCCCYC; Cell cycle checkpoint protein; Cell cycle checkpoint protein RAD17; HRAD 17; HRAD17;
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性能参数：

中文名称：细胞周期检控Rad17蛋白抗体（复制因子C）
英文名称：Anti-Rad17/RFC
别名：CCYC; Cell cycle checkpoint protein; Cell cycle checkpoint protein RAD17; HRAD 17; HRAD17;
包装号：G320
产地：中国大陆/进口产品
商标/品牌：Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商：田源试剂 TR、新试剂 NR
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产品详细描述

产品介绍：The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe Rad17, a cell cycle checkpoint gene required for cell cycle arrest ａnd DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C （RFC）, ａnd can form a complex with RFCs. This protein binds to chromatin prior to DNA damage ａnd is phosphorylated by ATR after the damage. This protein recruits the RAD1-RAD9-HUS1 checkpoint protein complex onto chromatin after DNA damage, which may be required for its phosphorylation. The phosphorylation of this protein is required for the DNA damage induced cell cycle G2 arrest, ａnd is thought to be a critical early event during checkpoint signaling in DNA damaged cells. Eight alternatively spliced transcript variants of this gene, which encode four distinct proteins, have been reported.Tissue Specificity : Overexpressed in various cancer cell lines ａnd in colon carcinoma （at protein level）. Isoform 2 ａnd isoform 3 are the most abundant isoforms in non irradiated cells （at protein level）. Ubiquitous at low levels. Highly expressed in testis, where it is expressed within the germinal epithelium of the seminiferous tubuli. Weakly expressed in seminomas （testicular tumors）.

细胞周期检控Rad17蛋白抗体（复制因子C）的质量标准：

■其它名称：	CCYC; Cell cycle checkpoint protein; Cell cycle checkpoint protein RAD17; HRAD 17; HRAD17;
■交叉反应：	hu, rat, mo
■产品类型：	一抗
■应用领域:	/肿瘤/免疫学/信号转导/细胞周期蛋白/转录调节因子
■蛋白分子：	predicted molecular weight: 75-80kDa
■浓度值：	1mg/1ml
■物理性状：	Lyophilized or Liquid
■免疫原：	KLH conjugated synthetic peptide derived from human Rad17
■亚型：	polyclonal
■纯化方法：	affinity purified by Protein A
■保存液：	0.01M PBS, pH 7.4 with 10 mg/ml BSA ａnd 0.1% Sodium azide
■应用技术：	//WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500（石蜡切片需做抗原修复）/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user.
■保存环境：	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

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质量投诉流程
1、向我们的客户服务部反应投诉原因及订单信息。
2、向我们发送投诉相关的证明材料。
3、田源时间进行质量投诉调查及处理调查结果。
4、田源将联系客户并提供质量投诉处理结果。

友情提醒：
部分进口产品投诉须按照进口产品要求的检测方法提供证据。
由于化学产品的特殊性，恕不接受以下投诉：
1、超过质量投诉期的进口产品投诉
2、非质量报告提及的指标投诉

细胞周期检控Rad17蛋白抗体（复制因子C）Anti-Rad17/RFC的相关产品目录：







1mg/1ml 细胞周期检控Rad17蛋白抗体（复制因子C） Anti-Rad17/RFC CCYC; Cell cycle checkpoint protein; Cell cycle checkpoint protein RAD17; HRAD 17; HRAD17;的来源为Rabbit，其相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗

查询其它抗体目录请点击本公司化工仪器网链接：http://www.chem17.com/st233816/erlist_675408.html

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