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生长抑素抗体 田源一抗
点击次数:172发布时间:2012/8/14 10:12:03
更新日期:2013/6/26 15:57:09
所 在 地:其它
产品型号:Anti-Somatostatin/GRIH
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详细内容
生长抑素抗体Anti-Somatostatin/GRIHGrowth hormone release inhibiting factor; SMS_HUMAN; Somatostatin-14; somatostatin SS14; S
360TIYO.COM-上海田源公司
性能参数:
中文名称:生长抑素抗体
英文名称:Anti-Somatostatin/GRIH
别名:Growth hormone release inhibiting factor; SMS_HUMAN; Somatostatin-14; somatostatin SS14; S
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:The cyclic tetradecapeptide somatostatin is widely distributed throughout the body and is an important regulator of endocrine and nervous system function. It exerts its biologic actions by binding to specific high affinity receptors on the cell surface. Somatostatin inhibits the release of somatotropin. Somatostatin has also been shown in sympathetic nerves, mucosal cells, myenteric nerves of the gastrointestinal tract, salivary glands and in some parafollicular cells of the thyroid. Somatostatin positive cells may also be present in medullary thyroid carcinomas, C cell hyperplasia, thymic and lung tumors and pulmonary small cell carcinomas. Subcellular Location : Secreted.Similarity : Belongs to the somatostatin family.生长抑素是胰岛D细胞的一种多肽激素,主要用于胰岛细胞的功能性分类和消化道粘膜中内分泌细胞及肿瘤的研究。 生长抑素在体内分布广泛。在神经系统中,广泛存在于中枢和外周神经系统,在脑内以下丘脑正中隆起的浓度为。在新皮层,边缘系统下杏仁核,海马等部位也广泛存在,以皮层含量。在脊髓后根和三叉神经神经节内的一级神经元中,亦含生长抑素的免疫反应性物质。生长抑素广泛存在于胃肠道粘膜的“D”细胞,以胃窦和胃体,在肠内越往下含量越低。“D”细胞有长的胞浆突起,在幽门腺区止于G细胞和“嗜铬细胞”,在泌酸腺区止于壁细胞和其他上皮细胞。生长抑素通过旁分泌机制由突起释放到G细胞和壁细胞膜上,抑制胃泌素和HCI分泌,在胰腺内,生长抑素由胰岛“D”细胞分泌,通过血液循环对胰岛及消化道起作用,作为旁分泌调节胰岛功能。 生长抑素的生理作用为:抑制垂体生长激素、促甲状腺激素、促肾上腺皮质激素和催乳类的释放,也抑制各种胃肠激素的释放,抑制胃泌素、促胰液素、胆囊收缩素、胃动素、胰多肽、胰高血糖素、肠高血糖素等的释放。同时也抑制胃酸、胃蛋白酶、胰蛋白酶及唾液淀粉酶的分泌。生长抑素抗体的质量标准:
■其它名称: | Growth hormone release inhibiting factor; SMS_HUMAN; Somatostatin-14; somatostatin SS14; S |
■交叉反应: | hu, mo, rat, chk, shp, pig, cow |
■产品类型: | 一抗 |
■应用领域: | /神经生物学/生长因子和激素 |
■蛋白分子: | predicted molecular weight: 13kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from human Somatostatin C-terminus |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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生长抑素抗体Anti-Somatostatin/GRIH的相关产品目录:
1mg/1ml 生长抑素抗体 Anti-Somatostatin/GRIH Growth hormone release inhibiting factor; SMS_HUMAN; Somatostatin-14; somatostatin SS14; S的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
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