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斯钙素抗体Anti-Stanniocalcin 1Stanniocalcin; STC; STC1.
360TIYO.COM-上海田源公司
性能参数:
中文名称:斯钙素抗体
英文名称:Anti-Stanniocalcin 1
别名:Stanniocalcin; STC; STC1.
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The gene contains a 5' UTR rich in CAG trinucleotide repeats. The encoded protein contains 11 conserved cysteine residues and is phosphorylated by protein kinase C exclusively on its serine residues. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Overexpression of human stanniocalcin 1 in mice produces high serum phosphate levels, dwarfism, and increased metabolic rate. This gene has altered expression in hepatocellular, ovarian, and breast cancers. [provided by RefSeq].STC1蛋白实在哺乳动物中发现的糖蛋白激素,参与机体的多种生理功能,不但可以通过肾脏和肠道系统来调节钙和磷酸盐的稳态,而且在促进脑神经元的终末分化、防止因大脑局部缺血造成脑神经元的损害、以及骨和肌肉的发育等方面也有重要作用.近来研究发现,STC-1在人类肿瘤的发生发展中也有着重要的作用.STC-1可作为一种稳定因子促进新生血管的成熟而发挥促肿瘤增殖生长,还可通过自分泌途经与肿瘤细胞表面的趋化因子和整合素相互作用,激活一系列细胞内信号,引起多种蛋白分泌,从而溶解细胞外基质屏障,使肿瘤发生侵润和转移。斯钙素抗体的质量标准:
■其它名称: | Stanniocalcin; STC; STC1. |
■交叉反应: | hu, rat, mo |
■产品类型: | 一抗 |
■应用领域: | /肿瘤/免疫学/神经生物学/信号转导/生长因子和激素/海洋生物 |
■蛋白分子: | predicted molecular weight: 28kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from human Stanniocalcin 1 |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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由于化学产品的特殊性,恕不接受以下投诉:
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斯钙素抗体Anti-Stanniocalcin 1的相关产品目录:
1mg/1ml 斯钙素抗体 Anti-Stanniocalcin 1 Stanniocalcin; STC; STC1.的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
查询其它抗体目录请点击本公司化工仪器网链接:http://www.chem17.com/st233816/erlist_675408.html
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