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TGF-β诱导早期应答基因1抗体 田源一抗
点击次数:122发布时间:2012/8/14 10:12:40
更新日期:2013/6/26 15:54:55
所 在 地:其它
产品型号:Anti-TIEG1/KLF10
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详细内容
TGF-β诱导早期应答基因1抗体Anti-TIEG1/KLF10TGF-beta inducible early growth response gene 1; Transforming growth factor-beta-inducible
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性能参数:
中文名称:TGF-β诱导早期应答基因1抗体
英文名称:Anti-TIEG1/KLF10
别名:TGF-beta inducible early growth response gene 1; Transforming growth factor-beta-inducible
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:KLF10 (Krueppel-like factor 10), also known as TIEG1, is a transcription factor that plays a role in the regulation of cell growth. It binds to the consensus sequence 5'-GGTGTG-3'. KLF10 plays a role in the response to TGFbeta (through the TGFbeta/Smad signalling pathway) and estrogen. In both cases, KLF10 induces or repressed gene transcription to enhance the TGFbeta/Smad signalling pathway, as well as other pathways, to regulate cell proliferation, differentiation and apoptosis. KLF10 has been shown to have a role in skeletal disease (osteopenia/osteoporosis), hypertrophic cardiomyopathy, and breast and prostate cancer. Subcellular Location : Nucleus.Similarity : Belongs to the Sp1 C2H2-type zinc-finger protein family. Contains 3 C2H2-type zinc fingers.TGF-β诱导早期应答基因1抗体的质量标准:
■其它名称: | TGF-beta inducible early growth response gene 1; Transforming growth factor-beta-inducible |
■交叉反应: | hu, mo, rat |
■产品类型: | 一抗 |
■应用领域: | /肿瘤/细胞生物/免疫学/神经生物学/信号转导/细胞凋亡/生长因子和激素 |
■蛋白分子: | predicted molecular weight: 53kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from human TIEG1 |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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TGF-β诱导早期应答基因1抗体Anti-TIEG1/KLF10的相关产品目录:
1mg/1ml TGF-β诱导早期应答基因1抗体 Anti-TIEG1/KLF10 TGF-beta inducible early growth response gene 1; Transforming growth factor-beta-inducible的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
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