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a-包衬蛋白抗体 田源一抗
点击次数:95发布时间:2012/8/14 10:14:15
更新日期:2013/6/26 15:52:23
所 在 地:其它
产品型号:Anti-SPECA
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详细内容
a-包衬蛋白抗体Anti-SPECAFodrin alpha chain; (ALPHA)II-SPECTRIN; Alpha II Spectrin; FLJ44613; Fodrin, alpha; NEAS;
360TIYO.COM-上海田源公司
性能参数:
中文名称:a-包衬蛋白抗体
英文名称:Anti-SPECA
别名:Fodrin alpha chain; (ALPHA)II-SPECTRIN; Alpha II Spectrin; FLJ44613; Fodrin, alpha; NEAS;
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:a-Fodrin is a universally expressed membrane associated cytoskeletal protein consisting of alpha and beta subunits. The protein is important for maintaining normal membrane structure and supporting cell surface protein function. Alpha Fodrin is one of the important targets cleaved by caspases during apoptosis. The full length 240 kDa protein can be cleaved at several sites within its sequence by activated caspases generating N terminal 150 kDa, C terminal 120 kDa, and 35 kDa major products. Cleavage of alpha Fodrin leads to membrane malfunction and cell shrinkage.Subcellular Location : Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Note=Expressed along the cell membrane in podocytes and presumptive tubule cells during glomerulogenesis and is expressed along lateral cell margins in tubule cells.Similarity : Belongs to the spectrin family.Contains 3 EF-hand domains.Contains 1 SH3 domain.Contains 23 spectrin repeats.Subunit : Like erythrocyte spectrin, the spectrin-like proteins are capable of forming dimers which can further associate to tetramers. Interacts with isoform 1 of ACP1. Interacts with CALM and EMD. Interacts (via C-terminal spectrin repeats) with TRPC4. Identified in a complex with ACTN4, CASK, IQGAP1, MAGI2, NPHS1 and SPTBN1.a-包衬蛋白抗体的质量标准:
■其它名称: | Fodrin alpha chain; (ALPHA)II-SPECTRIN; Alpha II Spectrin; FLJ44613; Fodrin, alpha; NEAS; |
■交叉反应: | hu, mo, rat, pig, cow, Rb, dog |
■产品类型: | 一抗 |
■应用领域: | |
■蛋白分子: | predicted molecular weight: 272kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from human SPECA |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //ELISA=1:500-1000//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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a-包衬蛋白抗体Anti-SPECA的相关产品目录:
1mg/1ml a-包衬蛋白抗体 Anti-SPECA Fodrin alpha chain; (ALPHA)II-SPECTRIN; Alpha II Spectrin; FLJ44613; Fodrin, alpha; NEAS; 的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
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