细胞信号转导分子Smad-2抗体Anti-Smad2Mothers against decapentaplegic homolog 2; SMAD 2; Mothers against DPP homolog 2; Smad2; h
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性能参数：

中文名称：细胞信号转导分子Smad-2抗体
英文名称：Anti-Smad2
别名：Mothers against decapentaplegic homolog 2; SMAD 2; Mothers against DPP homolog 2; Smad2; h
包装号：G320
产地：中国大陆/进口产品
商标/品牌：Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商：田源试剂 TR、新试剂 NR
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产品详细描述

产品介绍：SMAD2 or Mothers against decapentaplegic homolog 2 is a polypeptide that, as its name describes, is a homolog of the Drosophila gene: "Mothers against decepentaplegic". It belongs to the SMAD family of proteins, which belong to the TGF-Beta superfamily of modulators. Like many other TGF-Beta family members SMAD2 is involved in cell signalling. SMAD2 modulates signals of activin ａnd TGF-Beta＇s. It interacts with SMAD anchor for receptor activation （SARA）. The binding of ligands causes the phosphorylation of the SMAD2 protein ａnd the dissociation from SARA ａnd the association with SMAD4. It is subsequently transferred to the nucleus where it forms complexes with other proteins ａnd acts as a transcription factor. SMAD2 is a receptor regulated SMAD （R-SMAD） ａnd is activated by bone morphogenetic protein type 1 receptor kinase.This antibody is cross reactive with Smad3.转录调节因子（Transcriptin Regulators） Smads家族是发现的TGF-β信号转导途径中一个重要的新基因家族.是TGF-β特异的细胞内信号转导分子，SMAD2/3属于受体激活的SMADs。有学者认为：Smad2,Smad3在某些肿瘤中发生突变,有可能是一种肿瘤抑制基因。 Smad2/3蛋白与Smad1、Smad5有高度同源性。

细胞信号转导分子Smad-2抗体的质量标准：

■其它名称：	Mothers against decapentaplegic homolog 2; SMAD 2; Mothers against DPP homolog 2; Smad2; h
■交叉反应：	hu, mo, rat, cow, chk, dog, Rb
■产品类型：	一抗
■应用领域:	/肿瘤/细胞生物/信号转导/细胞凋亡/生长因子和激素/转录调节因子/激酶和磷酸酶
■蛋白分子：	predicted molecular weight: 52kDa
■浓度值：	1mg/1ml
■物理性状：	Lyophilized or Liquid
■免疫原：	KLH conjugated synthetic peptide derived from human Smad2 N-terminus
■亚型：	polyclonal
■纯化方法：	affinity purified by Protein A
■保存液：	0.01M PBS, pH 7.4 with 10 mg/ml BSA ａnd 0.1% Sodium azide
■应用技术：	//WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500（石蜡切片需做抗原修复）/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user.
■保存环境：	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

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细胞信号转导分子Smad-2抗体Anti-Smad2的相关产品目录：







1mg/1ml 细胞信号转导分子Smad-2抗体 Anti-Smad2 Mothers against decapentaplegic homolog 2; SMAD 2; Mothers against DPP homolog 2; Smad2; h的来源为Rabbit，其相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗

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