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磷酸化蛋白酪氨酸磷酸酶2抗体 田源一抗磷酸化抗体
点击次数:106发布时间:2012/8/14 10:16:39
更新日期:2013/6/26 15:47:54
所 在 地:其它
产品型号:Anti-Phospho-SHP2/SHIP2(Tyr477)
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详细内容
磷酸化蛋白酪氨酸磷酸酶2抗体Anti-Phospho-SHP2/SHIP2(Tyr477)PTPN11; BPTP 3; BPTP3; CFC; MGC14433; Noonan syndrome 1; Noonan syndrome 1 protein tyrosin
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性能参数:
中文名称:磷酸化蛋白酪氨酸磷酸酶2抗体
英文名称:Anti-Phospho-SHP2/SHIP2(Tyr477)
别名:PTPN11; BPTP 3; BPTP3; CFC; MGC14433; Noonan syndrome 1; Noonan syndrome 1 protein tyrosin
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:The steady state of protein tyrosyl phosphorylation in cells is regulated by the opposing action of tyrosine kinases and protein tyrosine phosphatases (PTPs). Several groups have independently identified a non transmembrane PTP, designated SHPTP1 (also known as PTP1C, HCP and SHP), which is primarily expressed in hematopoietic cells and characterized by the presence of two SH2 domains N terminal to the PTP domain. A second and much more widely expressed PTP with SH2 domains, SHPTP2 (also designated PTP1D and Syp), has been identified. SHP2 is a protein tyrosine phosphatase that is widely expressed and plays a regulatory role in various cell signaling events that are important for many cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration.SHP2(SH-PTP2)参与多种细胞内信号传导 如MAP kinase、 PI3k等途径,SHP2也是许多其他原癌基因信号通路的重要组成部分,在细胞的增殖及分化等过程扮演重要的角色.磷酸化蛋白酪氨酸磷酸酶2抗体的质量标准:
■其它名称: | PTPN11; BPTP 3; BPTP3; CFC; MGC14433; Noonan syndrome 1; Noonan syndrome 1 protein tyrosin |
■交叉反应: | hu, mo, rat |
■产品类型: | 一抗磷酸化抗体 |
■应用领域: | /肿瘤/免疫学/信号转导/转录调节因子/激酶和磷酸酶 |
■蛋白分子: | predicted molecular weight: 68kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated Synthesised phosphopeptide derived from human SHP2 around the phosphorylation site of Tyr477 |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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磷酸化蛋白酪氨酸磷酸酶2抗体Anti-Phospho-SHP2/SHIP2(Tyr477)的相关产品目录:
1mg/1ml 磷酸化蛋白酪氨酸磷酸酶2抗体 Anti-Phospho-SHP2/SHIP2(Tyr477) PTPN11; BPTP 3; BPTP3; CFC; MGC14433; Noonan syndrome 1; Noonan syndrome 1 protein tyrosin的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
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